Critical Review On Treatment And Treatment Of Hepatic Cirrhosis And Fibrosis

2382 Words Apr 24th, 2015 10 Pages
CRITICAL REVIEW ON TREATMENT AND PREVETION OF HEPATIC CIRRHOSIS AND FIBROSIS

INTRODUCTION
Liver cirrhosis is a common outcome in clinical progressions of all chronic liver diseases, distinguished by substitution of tissues of the liver by fibrous (scar) tissues. Regenerative nodules - lumps that appear in a bid to repair the damaged tissues – also replace the liver tissues, leading to an alteration of the liver structure to into structurally abnormal nodules. Liver fibrosis is as a resultant effect of the propagation of the process of healing of wounds, leading to fibrogenesis - an uncharacteristic obstinate process of connective tissue production and removal (Anthony, 1978).
It has been reported that cirrhosis occurs in roughly 20 % of individuals diagnosed with Hepatitis C Virus (HCV). But, this statistic is gotten from risk evaluations after 20 years of infection (Fattovich et al., 1997). And because HCV contraction can occur early in life through either contaminated medical equipment or injection drug usage, this makes the duration of infection often much longer than 20 years. Patterning data indicate that the risk of cirrhosis may surpass 40 % by 30 years of infection (Thein et al., 2008); nonetheless, exact data on the lifetime risk of cirrhosis are lacking. As regards potential hosts, age when infected are imperative with the 20-year accumulation of cirrhosis in chronic HCV varying from 5 % in patients who were infected before the age of 40 to 20 % in patients…

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