Pharmacology Research Assignment
Part A
Mary’s Conditions Clear, concise description of each condition at a pathophysiological level (2 each) Signs and symptoms that would be seen clinically (1 each) State which meds are taken for each condition (1 each) Explanation of how the drug relieves the symptoms of each condition at a physiological level (2 each) Comments/Mark hypertension a sustained, raised blood pressure over more than one reading (equal to or greater than 140/90 mm Hg (Lewis, 2014, p. 866)
Signs: truncal obesity, mental status changes, BP consistently >140 mm Hg systolic or 90 mm Hg diastolic
Symptoms: dyspnea, palpitations, anginal chest pain, fatigue, intermittent claudication, muscle cramps, nocturia, dizziness, blurred vision, paresthesias, erectile dysfunction, decreased libido
(Lewis, 2014, p. 884) metoprolol
&
HCTZ
metoprolol: blocks stimulation of beta …show more content…
349)
Ventolin: binds to beta2-adrenergic receptors in airway smooth muscle, leading to activation of adenyl cyclase and increased levels of cyclic-3’, 5’ (cAMP), resulting in decreased intracellular calcium that relaxes smooth muscle airways and bronchodilation
(Vallerand & Sanoski, 2017, p. 120) osteoarthritis a slow, progressive noninflammatory disorder of the synovial joints that results from cartilage damage triggered by a metabolic response at the chondrocyte level (Lewis, 2014, p. 1880) Signs: tenderness on palpation, pain with passive ROM, crepitus, joint enlargement, reduced joint motion, flexion contractures
Symptoms: joint pain, tenderness, grating sensation, stiffness
(O’Toole, 2017, p. 1291) acetaminophen inhibits synthesis of prostaglandins that may serve as mediators of pain and fever (CNS), resulting in analgesia and antipyresis
(Vallerand & Sanoski, 2017, p.
Part A
Mary’s Conditions Clear, concise description of each condition at a pathophysiological level (2 each) Signs and symptoms that would be seen clinically (1 each) State which meds are taken for each condition (1 each) Explanation of how the drug relieves the symptoms of each condition at a physiological level (2 each) Comments/Mark hypertension a sustained, raised blood pressure over more than one reading (equal to or greater than 140/90 mm Hg (Lewis, 2014, p. 866)
Signs: truncal obesity, mental status changes, BP consistently >140 mm Hg systolic or 90 mm Hg diastolic
Symptoms: dyspnea, palpitations, anginal chest pain, fatigue, intermittent claudication, muscle cramps, nocturia, dizziness, blurred vision, paresthesias, erectile dysfunction, decreased libido
(Lewis, 2014, p. 884) metoprolol
&
HCTZ
metoprolol: blocks stimulation of beta …show more content…
349)
Ventolin: binds to beta2-adrenergic receptors in airway smooth muscle, leading to activation of adenyl cyclase and increased levels of cyclic-3’, 5’ (cAMP), resulting in decreased intracellular calcium that relaxes smooth muscle airways and bronchodilation
(Vallerand & Sanoski, 2017, p. 120) osteoarthritis a slow, progressive noninflammatory disorder of the synovial joints that results from cartilage damage triggered by a metabolic response at the chondrocyte level (Lewis, 2014, p. 1880) Signs: tenderness on palpation, pain with passive ROM, crepitus, joint enlargement, reduced joint motion, flexion contractures
Symptoms: joint pain, tenderness, grating sensation, stiffness
(O’Toole, 2017, p. 1291) acetaminophen inhibits synthesis of prostaglandins that may serve as mediators of pain and fever (CNS), resulting in analgesia and antipyresis
(Vallerand & Sanoski, 2017, p.