Embryonic stem cells are from the earliest stage of human embryo that develop into eggs by in-vitro fertilization. Embryonic stem cells are derived from the blastocysts and are pluripotent instead of totipotent because they do not have the ability to become a part of the extra-embryonic membranes.
Pluripotent stem cells are capable of giving rise to any tissue, but not to functioning organisms. Induced pluripotent …show more content…
One difference between the two has to do with the amount of differentiated cell types that can be produced. Embryonic stem are pluripotent so they are capable of becoming any part of the body. Stem cells are limited to its differentiations from its origin. Since large numbers of stem cells are necessary for cell replacement therapies so embryonic stem cells are more efficient because it can be grown easily in …show more content…
The hydrogels were created with the specific task of cross-linking and switching the environment where the cells grow from an alginate dominated one to a collagen dominated one. Cells grew rapidly singularly until they grew into the other neighboring cells. It was lastly seen that timing of switching can influence the development of the cells; whether they become cardiac progenitor cells or specialized cardiomyocytes which can be utilized in regenerative medicine. (cite)
Cardiac cell differentiation
Through experimentation Xiaowu Sheng and his colleagues were able to utilize induced pluripotent stem cells and undifferentiated embryonic stem cells in order to observe variability among cardiac cells. Using induced pluripotent cells from human foreskin fibroblasts and a differentiation medium, they were able to culture and differentiate the cells into three types: pacemaker like, ventricular like and atrium