If there were less diseases, less people would have died. In documents A and E it says that about 80 people in Jamestown died in just two years from disease. It also says that many people got sick from the water because it wasn’t washing away their feces as well as they thought. With cleaner water and better medicines, less people would have died.
With better management of resources, there could have been less deaths. In document B it says that from years 1607-1612