Colorectal carcinoma is a cancer of the large intestine (colon) and rectum , the lower part of the digestive system. It can metastasis to liver, lung, bone, brain and lymph nodes. These are the common sites [8]. However, liver metastases is the main cause for death. Adrenal gland, testicular and skin are the less frequent sites(8). Usually, liver metastases are hypo vascular [5]. Colorectal cancer can be diagnosed by many modalities such as CT SCAN, FDG/PET And FDG PET/CT.
PET/CT is the most sensitive imaging modality for early detection of liver metastasis of gastrointestinal cancer. The two techniques are performed on the same equipment, the image known as fusion image. CT scanner is based on anatomical information. It grasps the main blood vessels inside the liver [5]. On the other hand, it has lower sensitivity as compared to FDG PET. It cannot distinguish bowel wall layers …show more content…
FDG/PET is the best method to detect recurrent colorectal carcinoma. FDG uptake increased in some organs such as, urinary bladder, ureters, kidneys [10]. Also in primary colorectal carcinoma. Macrophages, neutrophils, fibroblasts are the sites that FDG uptake accumulate in [3]. The disadvantage of FDG PET is that the spatial resolution is limited. Although, FDG PET may not detect small volume disease under 1 cm [8]. FDG PET tool considered as the most cost modality compared to the others. Hepatic surgical resection is first method used to improve quality of life [8]. The percentage of cure determined by the stage of the initial tumor. Tumor response depends on the change of tumor size. Chemotherapy was the choice in the past for patients with extensive liver metastases for example, adjuvant chemotherapy and to treat patients with colorectal liver metastases [7]. In pretreated patients there is decrease in FDG uptake which leads to poor result of
PET/CT is the most sensitive imaging modality for early detection of liver metastasis of gastrointestinal cancer. The two techniques are performed on the same equipment, the image known as fusion image. CT scanner is based on anatomical information. It grasps the main blood vessels inside the liver [5]. On the other hand, it has lower sensitivity as compared to FDG PET. It cannot distinguish bowel wall layers …show more content…
FDG/PET is the best method to detect recurrent colorectal carcinoma. FDG uptake increased in some organs such as, urinary bladder, ureters, kidneys [10]. Also in primary colorectal carcinoma. Macrophages, neutrophils, fibroblasts are the sites that FDG uptake accumulate in [3]. The disadvantage of FDG PET is that the spatial resolution is limited. Although, FDG PET may not detect small volume disease under 1 cm [8]. FDG PET tool considered as the most cost modality compared to the others. Hepatic surgical resection is first method used to improve quality of life [8]. The percentage of cure determined by the stage of the initial tumor. Tumor response depends on the change of tumor size. Chemotherapy was the choice in the past for patients with extensive liver metastases for example, adjuvant chemotherapy and to treat patients with colorectal liver metastases [7]. In pretreated patients there is decrease in FDG uptake which leads to poor result of