The most common side effect of colon cancer chemotherapeutic (CPT-11) is patients having severe diarrhea, caused by symbiotic bacterial β-glucuronidases. Which causes the drug to reactivate inside the gut. The enzymes were targeted without destroying bacteria that’s needed for human health. However, the purpose of these inhibitors is a way to prevent damage to mammalian cells that’s present in the intestines. If β-glucuronidase which causes the diarrhea isn’t inhibited the patients will have a higher risk of being infected and dehydrated. This is due to patients having a weak immune system due to their cancer and the bacteria that is essential to their human health becomes destroyed.
Introduction Cancer is a disease that could not only cause death, but always changes one’s physical appearance. However, there are many ways it could be prevented and also ways in which it could be cured, where it’s not as effective. Over the years researcher have been looking …show more content…
Based on result it shows that the presence of the inhibitor GDL patients having bloody stool due to CPT-11 can be lowered. For instance if CPT-11 treatment were to stop and patients using only the inhibitor, these a significant chance that having blood stool will perhaps become norm/ rare. The Other treatment options such as Kampo Therapy, a form of Chinese herb therapy, which helps with the side effects of chemotherapy. If successfully translated to humans, leads like those described here could allow dose intensification of CPT-11, enabling studies of whether efficacy could be improved in relevant human cancers by reducing one of the current dose-limiting side effects (Wallace 2010).With further studies test trail’s done of humans will be beneficial to show possible outcome of using GDL. Though test were initially done on mice the experiment was carried out as if it were to be done on
Introduction Cancer is a disease that could not only cause death, but always changes one’s physical appearance. However, there are many ways it could be prevented and also ways in which it could be cured, where it’s not as effective. Over the years researcher have been looking …show more content…
Based on result it shows that the presence of the inhibitor GDL patients having bloody stool due to CPT-11 can be lowered. For instance if CPT-11 treatment were to stop and patients using only the inhibitor, these a significant chance that having blood stool will perhaps become norm/ rare. The Other treatment options such as Kampo Therapy, a form of Chinese herb therapy, which helps with the side effects of chemotherapy. If successfully translated to humans, leads like those described here could allow dose intensification of CPT-11, enabling studies of whether efficacy could be improved in relevant human cancers by reducing one of the current dose-limiting side effects (Wallace 2010).With further studies test trail’s done of humans will be beneficial to show possible outcome of using GDL. Though test were initially done on mice the experiment was carried out as if it were to be done on