Human Ocular ciliary (CB) body is located between ora-serreta and iris which is multifunctional. Ciliary body consists of ciliary muscle and epithelial layer. The epithelial layer is again in two forms namely pigmented epithelial layer (PE) and non-pigmented epithelial layer (NPE). The anterior portion of CB continues with iris epithelium, posteriorly NPE continues with neurol retina and PE with retinal pigment epithelium. The important function of ciliary epithelium is to produce aqueous humor. Aqueous humor is required to build up the intraocular pressure (IOP), that maintains the eye shape, and also nourishes avascular eye tissues, like lens and cornea. Ciliary muscle helps for proper accommodation of lens (Janssen et al. 2012).
Previous studies reports , CB synthesizes and expresses multiple neuro endocrine proteins such as different as neurotensin, natriuretic peptides,and somatostatin, steroid-converting enzymes, transferrin, transthyretin,angiotensin, and growth factors(Coca-Prados and Escribano 2007) these endocrine molecules play role in regulating IOP, the composition of the aqueous humor. The ocular microenvironment of blood-aqueous barrier is anti-inflammatory, minimizes ocular tissue damage and restores vision clarity(Taylor 2009). …show more content…
NPE and PE also involved in a variety of metabolic process, including lipid and vitamin metabolism showed by gene functional studies
Formation of Aqueous by the Ciliary Epithelium aqueous humor production, depends on the interaction of complex mechanisms within the ciliary body, that involves blood flow, transcapillary exchange and transport processes in the ciliary
Previous studies reports , CB synthesizes and expresses multiple neuro endocrine proteins such as different as neurotensin, natriuretic peptides,and somatostatin, steroid-converting enzymes, transferrin, transthyretin,angiotensin, and growth factors(Coca-Prados and Escribano 2007) these endocrine molecules play role in regulating IOP, the composition of the aqueous humor. The ocular microenvironment of blood-aqueous barrier is anti-inflammatory, minimizes ocular tissue damage and restores vision clarity(Taylor 2009). …show more content…
NPE and PE also involved in a variety of metabolic process, including lipid and vitamin metabolism showed by gene functional studies
Formation of Aqueous by the Ciliary Epithelium aqueous humor production, depends on the interaction of complex mechanisms within the ciliary body, that involves blood flow, transcapillary exchange and transport processes in the ciliary