Chronic Obstructive Pulmonary Disorder (COPD) is a disease affecting the lungs, creating an airway limitation that is usually progressive, poorly reversible and accompanied by an increased or abnormal inflammatory response to the inhalation of toxic agents. This response can lead to a series of conditions that contribute in different ways to the development of COPD. They are known as chronic bronchitis, emphysema or bronchiliotis. Chronic bronchitis is defined by the presence of inflammation in the central airways that leads in an increased sputum production. It is still debatable whether sputum hypersecretion is actually related to airflow limitation. Findings from Peto et. al. suggest that they are two independent diseases with different
