349)
Ventolin: binds to beta2-adrenergic receptors in airway smooth muscle, leading to activation of adenyl cyclase and increased levels of cyclic-3’, 5’ (cAMP), resulting in decreased intracellular calcium that relaxes smooth muscle airways and bronchodilation
(Vallerand & Sanoski, 2017, p. 120)
osteoarthritis a slow, progressive noninflammatory disorder of the synovial joints that results from cartilage damage triggered by a metabolic response at the chondrocyte level (Lewis, 2014, p. 1880) Signs: tenderness on palpation, pain with passive ROM, crepitus, joint enlargement, reduced joint motion, flexion contractures
Symptoms: joint pain, tenderness, grating sensation, stiffness
(O’Toole, 2017, p. 1291) acetaminophen inhibits synthesis of prostaglandins that may serve as mediators of pain and fever (CNS), resulting in analgesia and antipyresis
(Vallerand & Sanoski, 2017, p.…