Four layers compose the esophagus including the mucosa, submucosa, muscularis propria, and adventitia. The mucosa, the innermost layer, is composed of three sub-layers, the epithelium, lamina propria, and muscularis mucosa. Esophageal cancers typically begin in the epithelium of the mucosa, where squamous cells are located. Blood vessels and nerves of the esophagus are found under the mucosa, in the submucosa. The muscularis propria is composed of muscles and allows the esophagus to propel food from the throat towards the stomach. Lastly, the outer layer of the esophagus, the adventitia, is made of connective tissues and helps to bind structures and organs in the pleural cavity to one another (American Cancer Society,
Four layers compose the esophagus including the mucosa, submucosa, muscularis propria, and adventitia. The mucosa, the innermost layer, is composed of three sub-layers, the epithelium, lamina propria, and muscularis mucosa. Esophageal cancers typically begin in the epithelium of the mucosa, where squamous cells are located. Blood vessels and nerves of the esophagus are found under the mucosa, in the submucosa. The muscularis propria is composed of muscles and allows the esophagus to propel food from the throat towards the stomach. Lastly, the outer layer of the esophagus, the adventitia, is made of connective tissues and helps to bind structures and organs in the pleural cavity to one another (American Cancer Society,