Chemical Compounds That Are Derivatives Of Vitamin A? Essay example

1072 Words Dec 15th, 2016 5 Pages
Tretinoin, or all-trans-retinoic acid, is a retinoid that belongs to a class of chemical compounds that are derivatives of vitamin A, the main component of this generic pharmaceutical form of retinoic acid. Developed in the late 1960s by James Fulton and Albert Kligman from the University of Pennsylvania, tretinoin was created to treat acne vulgaris. Since then, tretinoin cream has been proven to successfully treat a variety of other skin conditions like reversing the effects of photo-aging, mottling or hyperpigmentation, scars and stretch marks. Tretinoin has also been proven to be effective for countering signs of aging on surface skin because it can minimize fine lines and wrinkles.

General Information on Tretinoin and Tretinoin Cream
When Fulton and Kligman developed the chemical formula of tretinoin for the treatment of acne vulgaris, it soon came to be known by the brand name Retin-A, which was the first of all brand name tretinioin creams to be produced. The University of Pennsylvania held the patent for the tretinoin cream, which it licensed to US pharmaceutical companies like Ortho-McNeil Pharmaceuticals who manufactures Retin-A, Retin-A Micro and Renova. There are several other tretinoin creams that have been manufactured as an alternative to Retin-A, such as: Atralin by Valeant Pharmaceuticals International, Inc., Avita by Mylan Bertek Pharmaceuticals, Refissa by Spear Pharmaceuticals and Tretin-X by Mylan Bertek Pharmaceuticals.

Retin- A Or Retinoic Acid
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