Chapter 13 Review Essays

9111 Words Dec 2nd, 2012 37 Pages
When lactose becomes available the genes encoding β-galactosidase and lactose permease are upregulated in E. coli.

true 2
Different globin polypeptides are expressed at similar levels during the embryonic and fetal stages of mammalian development.

false 3
RNA polymerase can bind to the promoter region of the DNA even when the lac repressor is bound to the operator site.

true Hide
4
Both eukaryotes and prokaryotes require a promoter region for gene transcription.

true 5
Eukaryotic genes are almost always organized in groups, similar to operons in prokaryotes.

false Advertisement
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6
Unmethylated CpG islands are correlated with inactive
…show more content…
31
Which of the following would NOT be associated with a positive regulation mechanism?

corepressor 32
In the lac operon, when allolactose binds to the repressor protein, the repressor protein

is prevented from binding to the operator 33
Catabolite repression of the lac operon

involves cyclic AMP (cAMP) levels. 34
Which of the following statements is true regarding the lac operon?

LacZ, lacY, and lacA gene products are synthesized at very low levels, even without lactose present. 35
The lacI gene encodes a(n) __________ of the lac operon.

repressor 36
2 domains of Regulatory tf
- DNA binding
- small effector molecule binding 37
Group of structural genes under transcriptional control of one promoter operon 38
Lac operon
- in e. coli
- 3 structural genes: lacZ, lacY, lacA 39
LacZ
B-galactosidase 40
LacY
lactose permease (uptake of lactose from outside of cell) 41 lacA galactosidase transacetylase 42
2 regulatory sites by lac promoter lacO CAP site 43 lacO operator- provides bidnign site for repressor protein 44
CAP site activator biding site 45
LacI gene codes for lac repressor 46
Who studied rare mutants with abnormal lactose use
Jacob, Monod and

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