Causes Of Renal Failure

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Renal Failure

History and symptoms - intrarenal acute renal failure
Mr. Donovan’s condition is consistent to intrarenal acute renal failure. Due to his history with renal insufficiency and uncontrolled hypertension, it is more likely that he is suffering from intrarenal acute kidney injury. The patient has no history obstruction (postrenal) or with trauma (prerenal). Hypertension, as shown by the patient, is seen with an intrarenal acute renal failure while hypotension is seen in prerenal and cardiovascular problems are not seen in postrenal acute renal failure (Mehta et al., 2011). There is a decrease in pressure in the renal arteries, which reduce the kidney’s ability to function effectively. Consequently, there
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However, ischemia-caused ATN is the main contributor of intrarenal acute renal failure (Mehta et al., 2011). Postischemic ATN may result and cause hypotension, hypoperfusion, and hypoxemia. Consequently, there will be a decline in ATP production and increases in toxic oxygen-free radicals, which predisposing antioxidant protection, tissue swelling, injury and necrosis.
Impairment of the proximal tubular epithelium disrupts the transport of molecules. The highest damage is noted on the outer medulla, with necrosis ate the cortex and loss of cells in the tubular epithelium (Bellomo, Kellum, & Ronco, 2012). Nephrotoxic ATN is caused by many antibiotics, particularly the aminoglycosides. The renal failure may be seen just after treatment. Additionally, this ATN condition may be caused by radiocontrast (Coca, 2012). Conditions that may exacerbate the condition with radiocontrast and aminoglycosides are diabetes mellitus, old age, dehydration and significant renal insufficiency. The patient has SOB, cardiovascular disease of HTN, fatigue and pedal edema, which indicates fluid retention that may result in CHF. Intra acute kidney injury may be caused by condition characterized by ischemia or dysfunction in the kidney
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The recovery of the condition is proportional to the time of obstruction. You may use Renal ultrasonography to examine the patient for hydronephrosis because it uses no contrast dye, which implies that the renal function is not affected.
Health determinants that may lead to renal failure.
The health determinants that may affect the development of renal failure include hydration level, dietary habits, cardiac function, use of medication, immune system status, genetics, and endocrine function. For example, congestive heart failure can affect the blood pressure and volume in the kidneys. Additionally, diabetes mellitus may predispose renal damage due the continuously elevated glucose levels in the blood. Consequently, an individual’s health status determines the level of pressure their renal system prior to causing irreversible renal conditions.
EBP data - pharmacologic and pathophysiology issues at Mr. Donovan 's

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