There are two main factors causing chronic obstructive pulmonary disease which is external factor and internal factor. Internal factors normally is related to inner of a person, whereas, external factors are influenced by outside factors that leaves an impact on a person. Internal factor includes cigarette smoking, pipe, cigar, and other types of tobacco smoke. Childhood respiratory infection, and Alpha1-antitrypsin deficiency also contributes to internal factor.The external factor includes second-hand smoke, inhaling pollutants. Besides second-hand smoking, fumes, chemicals and dust found in many work environments are contributing factors for many individuals who develop COPD. Indoor air pollution …show more content…
In the vast majority of cases, the lung damage that leads to COPD is caused by long-term cigarette smoking. But there are likely other factors at play in the development of COPD, such as a genetic susceptibility to the disease, and smoking is thought to be responsible for around 90% of cases. The likelihood of developing COPD is increased by often smoking and longer duration of smoking. This is due to smoking irritates and inflames the lungs, which results in scarring. Over many years, the inflammation leads to permanent changes in the lung. The walls of the airways thicken and more mucus is produced. Damage to the delicate walls of the air sacs in the lungs causes emphysema and the lungs lose their normal elasticity. The smaller airways also become scarred, narrowed, and damage cannot be …show more content…
Inherited factors (genes), including alpha-1 antitrypsin deficiency. This is a rare condition in which your body may not be able to make enough of a protein (alpha-1 antitrypsin) that helps protect the lungs from damage. This uncommon, inherited disorder increases the risk of lung and liver disease. People who have this disorder and who smoke generally start to have symptoms of emphysema in their 30s or 40s. Those who have this disorder but don't smoke generally start to have symptoms in their 80s. Alpha-1 can only be diagnosed with a blood test. Moreover, childhood respiratory infection is one of the causes as well. Evidence suggests that colds and respiratory viruses in childhood, especially before age 2, may decrease lung function and increase the risk of developing breathing problems and COPD in