Caffeine Is A Competitive Inhibitor Of Adenosine Essay

1657 Words May 5th, 2016 null Page
Most of us consume caffeine in numerous and assorted forms, whether chocolate, soda, coffee, tea, or energy drinks. Everyone ingests it in some shape or form. But what happens when we consume the caffeinated product? Briefly, before getting into all the biochemistry, caffeine is a competitive inhibitor of adenosine. In fact, according to Reginald Garrett and Charles Grisham, “Caffeine mainly acts by blocking adenosine receptors and thus bring about changes in the levels of various neurotransmitters like dopamine, adrenaline, and glutamate” (Garret & Grisham 312). This means that when caffeine runs through the body, caffeine outcompetes the adenosine and occupies the active site of the enzyme phosphodiesterase, which would typically degrade adenosine. When this occurs the cerebral blood flow is proportional to the amount of caffeine consumed, and as a result, there is an increase in efficiency with neurotransmitters in the cerebral cortex. This results in improvements with alertness, problem-solving, decision-making, concentration and neuromuscular coordination. Alas, coffee also causes negative effects especially with overconsumption which cause dehydration, increase osteoporosis (5 mg of calcium, magnesium, and potassium lost in urine), increased digestive discomfort such as indigestion or heartburn, and other cons such increased LDL cholesterol levels have been noted. With this in mind, we have all seen the drinks NeuroSonic, Red Bull, Monster, or 5-hour energy, the…

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