Bertini et al. (2013) reported about exhaled breath condensate metabolomics in COPD patients using NMR.
The study included 37 patients and 25 healthy subjects. The patients displayed significantly lower levels of acetone, valine and lysine, and significantly higher levels of lactate, acetate, propionate, serine, proline and tyrosine. Samples of saliva were obtained shortly before the EBC sampling to detect possible salivary contaminations. By comparing the spectra from EBC and saliva in the same subject, they excluded any significant salivary contamination of EBC.
There is evidence of abnormal muscle bioenergetics in
COPD patients. For this reason, Rodrı´guez et al. (2011) studied the effects of exercise on plasma metabolic profile in COPD
The study included 37 patients and 25 healthy subjects. The patients displayed significantly lower levels of acetone, valine and lysine, and significantly higher levels of lactate, acetate, propionate, serine, proline and tyrosine. Samples of saliva were obtained shortly before the EBC sampling to detect possible salivary contaminations. By comparing the spectra from EBC and saliva in the same subject, they excluded any significant salivary contamination of EBC.
There is evidence of abnormal muscle bioenergetics in
COPD patients. For this reason, Rodrı´guez et al. (2011) studied the effects of exercise on plasma metabolic profile in COPD