3. CAC hypothetical enzyme defect When an alpha ketoglutarate dehydrogenase enzyme is removed or defective, it cannot convert alpha ketoglutarate substrate to succinyl-CoA product in the citric acid cycle. Thus, the whole citric acid cycle will not continue to function. The steps of citric acid cycle will not continue once there will be a defective enzyme.
Normally, NADH and FADH2 in the matrix carry electrons to deliver them in the inner membrane of mitochondria. NADH delivers electrons in the electron transport chain complex I and FADH2 delivers electrons in complex II. Then, the coenzyme Q10 will pick up the electron and transfer it to complex III. Then, another coenzyme called cytochrome complex (Cyt C) will deliver the electron to complex IV. This …show more content…
Then, another coenzyme called cytochrome complex (Cyt C) will deliver the electron to complex IV. This series of compounds that transfer electrons is called electron transport chain. When the electron reached the complex IV, electron will be released so other electrons can go through and will be obtained by oxygen (O2) to form into water (H2O). Oxygen also called terminal electron acceptor is necessary to remove electrons so other electrons can go through and to pump out protons (H+) for cellular respiration. An enzyme called ATP synthase provided protons energy to make ATP. Protons can only go through ATP synthase in a controlled way to go to the matrix of a mitochondria. ATP synthase makes ATP from adenosine diphosphate (ADP) and inorganic phosphate (Pi). In a process called oxidative phosphorylation, ATP is formed as a result of transfer of electrons from NADH and FADH2 to O2 by a series of electron carriers. Together, electron transport chain and oxidative phosphorylation makes ATP in aerobic metabolism (Sanders,
Normally, NADH and FADH2 in the matrix carry electrons to deliver them in the inner membrane of mitochondria. NADH delivers electrons in the electron transport chain complex I and FADH2 delivers electrons in complex II. Then, the coenzyme Q10 will pick up the electron and transfer it to complex III. Then, another coenzyme called cytochrome complex (Cyt C) will deliver the electron to complex IV. This …show more content…
Then, another coenzyme called cytochrome complex (Cyt C) will deliver the electron to complex IV. This series of compounds that transfer electrons is called electron transport chain. When the electron reached the complex IV, electron will be released so other electrons can go through and will be obtained by oxygen (O2) to form into water (H2O). Oxygen also called terminal electron acceptor is necessary to remove electrons so other electrons can go through and to pump out protons (H+) for cellular respiration. An enzyme called ATP synthase provided protons energy to make ATP. Protons can only go through ATP synthase in a controlled way to go to the matrix of a mitochondria. ATP synthase makes ATP from adenosine diphosphate (ADP) and inorganic phosphate (Pi). In a process called oxidative phosphorylation, ATP is formed as a result of transfer of electrons from NADH and FADH2 to O2 by a series of electron carriers. Together, electron transport chain and oxidative phosphorylation makes ATP in aerobic metabolism (Sanders,