The first type of Burkitt lymphoma to arise was endemic. This type has a large presence in underdeveloped countries such as central Africa and Papua New Guinea. This lymphoma was first discovered by British surgeon Denis Parsons Burkitt, which is where its name comes from (Gera, Saah, & Scott-Emuakpor, 2012, para. 2). He studied tumors in jaws of young children in African regions and found them to be caused by this unique type of lymphoma. It was in 1961 after more extensive research that he found an association between Burkitt lymphoma and Epstein-Barr virus (EBV) (Gera et al., 2012, para. 2)
Pathological process is an intrinsic subject that is important in explanation of the overall pathology. Understanding that there is a presence of EBV …show more content…
Blood work is done and shows leukocytosis and anemia, both indications of Burkitt lymphoma. An ultrasound guided biopsy of lymph nodes of the neck and spine is completed and sent to the lab. In addition, a CT chest for pulmonary embolus is performed showing splenomegaly and axillary/mediastinal adenopathy. The lymph nodes shown in the CT also show bilateral hilar and mediastinal adenopathy. No acute central pulmonary embolus is found. Both of those also point to a type of lymphoma being present. He is then diagnosed with stage IV Burkitt lymphoma and chooses to undergo Intrathecal chemotherapy through lumbar puncture. The patient developed tumor lysis syndrome and was readmitted into the hospital two months after the initial diagnosis. Though Burkitt lymphoma is rare in adults and not often present in the U.S., it is very common in other regions of the world such as Africa and Papua New Guinea. It is a very complex type of lymphoma composed of three different types; endemic, sporadic, and HIV associated. It is important to know the symptoms, stages, radiographic manifestations, and treatment options for this
Pathological process is an intrinsic subject that is important in explanation of the overall pathology. Understanding that there is a presence of EBV …show more content…
Blood work is done and shows leukocytosis and anemia, both indications of Burkitt lymphoma. An ultrasound guided biopsy of lymph nodes of the neck and spine is completed and sent to the lab. In addition, a CT chest for pulmonary embolus is performed showing splenomegaly and axillary/mediastinal adenopathy. The lymph nodes shown in the CT also show bilateral hilar and mediastinal adenopathy. No acute central pulmonary embolus is found. Both of those also point to a type of lymphoma being present. He is then diagnosed with stage IV Burkitt lymphoma and chooses to undergo Intrathecal chemotherapy through lumbar puncture. The patient developed tumor lysis syndrome and was readmitted into the hospital two months after the initial diagnosis. Though Burkitt lymphoma is rare in adults and not often present in the U.S., it is very common in other regions of the world such as Africa and Papua New Guinea. It is a very complex type of lymphoma composed of three different types; endemic, sporadic, and HIV associated. It is important to know the symptoms, stages, radiographic manifestations, and treatment options for this