Bubonic Plague: A Case Study

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When the bubonic plague had the most impact in medieval times it had tremendous psychological impact on those that were infected and those who were not. In those times people believe it was god bringing about a great pestilence for those who sinned. With more and more people dying everyday people turned away or toward the church to try and repent for their sins and seal their way into heaven. In fact, the onset of this bacterium was so severe that people began to blame Jews for the reason why this pestilence has plagued their land. The people living at the time had a dark view on life because the plague seemed unstoppable and unrelenting in its pursuit.
HIV-Aids history dates back farther than many believe and originate from a close relative
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These treatments are categorized as well. The first category is called Non-nucleoside reverse tripticase inhibitors or (NNRTI). This specific drug works by disabling the protein HIV viruses need to make copies of itself. Without this protein the HIV virus replication process is slowed but not halted. Specific drugs that carry out this process include efavirenz (Sustiva) and etravirine (Intelence) among others (Mayo clinic 2015). Another category that works by posing as faulty building blocks that the virus needs to replicate. This drug is called Nucleoside or nucleotide reverse transcriptase inhibitors. Examples of this drug includes Abacavir (Ziagen), and the combination drugs emtricitabine-tenofovir (Truvada), and lamivudine-zidovudine (Combivir) (Mayo Clinic 2015). Another way of slowing this disease includes Protease inhibitors or (PI). These drugs work by disabling or breaking up the protein protease which is another protein that HIV viruses need to start replication. The fourth medicinal treatment slows the onset of HIV/AIDs by blocking the virus from entering the CD4 cells altogether. The entry or fusion inhibitor treatment has proven to be the most successful treatment thus far but alas still does not cure the disease. Examples of medications in this treatment includes enfuvirtide (Fuzeon) and maraviroc (Selzentry) (Mayo clinic 2015). Lastly the final treatment proven to slow HIV/Aids is called integrase inhibitors. This treatment prevent the virus by breaking down or disabling integrase, which is a protein needed by the virus to insert its genetic material into the CD4 cells’ nucleus. Overall, there are a number of ways to slow down the virus in every stage of its replication process, but unfortunately none has shown to completely stop the onset of AIDS and eventually

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