The toxin was first discovered in 1735 Europe as it caused a fatal disease of the nervous system. Its cause was suspected to be connected to German Sausages. This is originally where its name came from, as due to these suspicions the toxin was named “botulus” – the Latin for sausage.
Since then we know that Botulinum Toxin is a potent neurotoxin that is produced by rod-shaped spore-forming anaerobic bacterium called Clostridium bacterium. The bacterium require special conditions to reproduce; usually low-levels or no oxygen and low acidity (nothing above pH 5.4). If the toxin was to be consumed, once absorbed by the intestine it gets into the bloodstream via simple diffusion. From there the toxin moves to attack the nervous system causing …show more content…
From their report, it is established that “botulinum toxin type A is an alternative treatment, particularly for HFS patients who are elderly, or considered high risk for the MVD operation under general anaesthesia”.[6] Statistical analysis shows that from the comparative analysis using the paired t-test, the data are reported as the Statistical significance at p<0.05. The margin here is small thus suggesting a positive outcome and therefore providing evidence that the toxin is a successful therefore when used correctly it can improve the quality of life.From the results using electrophysiological examination that was performed before, 2 and 6 weeks after Botox treatment, HFS was improved in the oculi muscle more than in the oris or mentalis muscles. For all patients, the outcome at 6 weeks following the treatment was superior to that observed at 2 weeks post-treatment. This suggests that a 6 week use of the toxin can not only be more effective than the operation but also proves the use of the toxin will work effectively opening a variety of future paths for the toxin.
Since then we know that Botulinum Toxin is a potent neurotoxin that is produced by rod-shaped spore-forming anaerobic bacterium called Clostridium bacterium. The bacterium require special conditions to reproduce; usually low-levels or no oxygen and low acidity (nothing above pH 5.4). If the toxin was to be consumed, once absorbed by the intestine it gets into the bloodstream via simple diffusion. From there the toxin moves to attack the nervous system causing …show more content…
From their report, it is established that “botulinum toxin type A is an alternative treatment, particularly for HFS patients who are elderly, or considered high risk for the MVD operation under general anaesthesia”.[6] Statistical analysis shows that from the comparative analysis using the paired t-test, the data are reported as the Statistical significance at p<0.05. The margin here is small thus suggesting a positive outcome and therefore providing evidence that the toxin is a successful therefore when used correctly it can improve the quality of life.From the results using electrophysiological examination that was performed before, 2 and 6 weeks after Botox treatment, HFS was improved in the oculi muscle more than in the oris or mentalis muscles. For all patients, the outcome at 6 weeks following the treatment was superior to that observed at 2 weeks post-treatment. This suggests that a 6 week use of the toxin can not only be more effective than the operation but also proves the use of the toxin will work effectively opening a variety of future paths for the toxin.