Paget's Disease: The Skeletal System

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The skeletal system is known as the support system of the body that also provides protection of the internal organs. The skeletal system consists of bones, cartilage, ligaments, and tendons (Tortora and Derrickson 2014). “The study of bone structure and the treatment of bone disorders is called osteology” (Tortora and Derrickson 2014). Bone is made of various tissues working together, and because of this, bones are thought of as organs (Tortora and Derrickson 2014).
Bones are constantly going through a process of breaking down and building new bone tissue, which is also known as remodeling (Tortora and Derrickson 2014). The skeletal system has six main functions, which consists of support, protection, helping with movement, mineral homeostasis,
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Paget’s disease of the bone is a disorder that has to do with the remodeling process of the bones throughout the skeleton (Ralston 2013). This disorder is osteoclast-mediated resorption causing an osteoblast-mediated bone repair (Whyte 2006). Due to this, Paget’s disease causes the bone to grow larger in size, yet at the same time, also causing the bone to become weak and brittle. Typically this disease happens to older people (Ralston 2013). People who have this disease can have bone pain that is a cause of join pain or stiffness, leg deformities caused by deformities in the bone, skull deformities, fractures, headaches, and hearing loss (Wisse 2013). This disease can be diagnosed with bone scans and bone x-rays and tests that would follow would be the alkaline phosphatase isoenzyme and serum calcium (Ralston 2013). When a patient with Paget’s disease is in need of treatment, this means that the person is having bone issues because of the size, weight, or shape, and additionally if the skull has been affected by this disease (Ralston 2013). Drug therapy is in order to help prevent the bone from continuous remodeling (Wisse 2013). Bisphosphonates would help reduce bone remodeling, and this drug can be given taken through the mouth or injected (Wisse 2013). Calcitonin would be another treatment in that this would be a hormone that helped with the bone metabolism; this drug can be taken as a nasal spray or injection (Wisse 2013). Only in severe cases will surgery be in order, but a person is able to take pain medication to help reduce pain (Wisse

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