Bone Repair
Broken or fracture bone have four (4) stages to repair.
1.Hemata formation - due to fractured bone, the blood vessels are also ruptured and caused hematoma formation and inflammation. This allow clotting process and bone cells die at the broken ends. These dead bone cells are remove by osteoclasts.
2.Bone generation - phagocytic cells clear away the dead cells and capillaries grow again. Fibroblast produce collagen fibers that connect the broken bone ends, while osteoblasts start to form spongy bone, these two enter the area. The repair tissue (fibrocartilaginous callus) is composed of both hyaline and fibrocatilage.
3.Bony callous formation - fibrocatilaginous callus is converted into bony callus. It takes 3-4 months for broken bone ends joined together …show more content…
It last until the bone has completely returned to its original morphology.
Bone Remodelling
Bone remodeling happens throughout person’s life to adjust bone architeture, to replace old bone, and also to maintain plasma calcium homeostasis. If there is not enough calcium in the body, the parathyroid hormone is released to breakdown bone matrix to release calcium (and remodeling).
It is consists three (3) phases: a) resoprtion: involves the removal of mineralized bone done by the osteoclasts, bone-destroying cells. Old bones are beng digest. b) reversal - mononuclear cells appear on the bone surface. c) formation - osteoblasts, bone-forming cells, form new bone until the resorbed bone is replaced.
Hematopoiesis
The prduction of all blood cells. It involves forming, developing and maturing into their final adult types. It starts with hematopoietic stem cell and then becoming a mature blood type such as red blood cells, white blood cell or some other type. It happens in the red bone marrow, hemopoietic stem cells (hemoytoblasts) divide to produce various blast cells. It matures and becomes a particular blood
Broken or fracture bone have four (4) stages to repair.
1.Hemata formation - due to fractured bone, the blood vessels are also ruptured and caused hematoma formation and inflammation. This allow clotting process and bone cells die at the broken ends. These dead bone cells are remove by osteoclasts.
2.Bone generation - phagocytic cells clear away the dead cells and capillaries grow again. Fibroblast produce collagen fibers that connect the broken bone ends, while osteoblasts start to form spongy bone, these two enter the area. The repair tissue (fibrocartilaginous callus) is composed of both hyaline and fibrocatilage.
3.Bony callous formation - fibrocatilaginous callus is converted into bony callus. It takes 3-4 months for broken bone ends joined together …show more content…
It last until the bone has completely returned to its original morphology.
Bone Remodelling
Bone remodeling happens throughout person’s life to adjust bone architeture, to replace old bone, and also to maintain plasma calcium homeostasis. If there is not enough calcium in the body, the parathyroid hormone is released to breakdown bone matrix to release calcium (and remodeling).
It is consists three (3) phases: a) resoprtion: involves the removal of mineralized bone done by the osteoclasts, bone-destroying cells. Old bones are beng digest. b) reversal - mononuclear cells appear on the bone surface. c) formation - osteoblasts, bone-forming cells, form new bone until the resorbed bone is replaced.
Hematopoiesis
The prduction of all blood cells. It involves forming, developing and maturing into their final adult types. It starts with hematopoietic stem cell and then becoming a mature blood type such as red blood cells, white blood cell or some other type. It happens in the red bone marrow, hemopoietic stem cells (hemoytoblasts) divide to produce various blast cells. It matures and becomes a particular blood