Biology Quiz

Great Essays
1. What is the species name of the model/study organism? If the study is looking at human disease choose the disease causing organism. If the study is on some aspect of human physiology or anatomy, the model organism is a human.
The study followed one White family and one Italian family to see how the mutation of a Manganese Transporter, SLC30A10, causes a variety of diseases such as Parkinson’s and Chronic Liver Disease. The model organism of the study is the Homo sapien.
2. Intellectual merit and broader impact: A) What did the authors feel this research was important enough to spend time and money doing it B) Is there an economic, environmental, medical, health, or a combination of reasons that makes this research valuable? -I feel that
…show more content…
Sampling for the study: A. Where did they sample? For the study men from both Italy and Holland had their Genomic DNA sampled. Samples of tissue for the immunohistochemistry experiment were taken from a brain bank and a Depart of Pathology at a school in the Netherlands. B. How did they sample? Fancy systems that are used for genotyping were used to analyze the DNA. Homozygosity which is having identical alleles in a single chromosome was another factor of the DNA that was analyzed (In Encyclopedia Britannica Academic online). Exome sequencing was used to organize the parts of DNA. An Exome is the coding part of DNA which would be a nightmare to look at if cluttered (“Exome,” 2017). Lastly the Exons of the mutated SLC30A10 were compared to the exons of healthy SLC30A10. C. Number of Samples taken? Unclear the number of samples taken, but there were five men who participated in the study and four follow ups on their condition. The number of tissue samples for the other experiments was also not clear in the …show more content…
Before the study, it was a bit fuzzy as to whether not SL30A10 was a transporter or not, but now the results from staining test make it know that it is in fact a transporter of Manganese. The fact that it is a transporter also explains why it is in so many different tissue types. The surprising discovery to the researchers was the fact that SL30A10 was in incredibly small amounts where there was supposed to be an abundance of it. This supports the hypothesis in saying that the SL30A10 is mutated. It was also surprising for the researchers to find zinc more prevalent in the tissues where Manganese was supposed to be. This further supports the hypothesis because of the differences between the healthy tissue and unhealthy tissue. Because of the abnormal amounts of manganese caused by SL30A10 in the nervous system and liver it proves that this mutation plays a huge role in the causation of Parkinson’s and Liver Disease. Overall the Researchers have enough to approve of their hypothesis just with the immunohistochemistry study

Related Documents

  • Decent Essays

    Biology Quiz

    • 374 Words
    • 2 Pages

    Page 1 : http://mw2.concord.org/public/part2/intromacro/page1.cml 1. The individual DNA strands, which are macromolecules, are seen most clearly at 10 to the power of (a) -3 (b) +4 (c) -8 (d) -23 My answer is (c) (2:16:56 PM) 2. How many powers of ten are there between the DNA strands and you? Hint. (a) 3 (b) 6 (c) 8 (d) 12 My answer is (c) (2:17:22 PM) Page 2 : http://mw2.concord.org/public/part2/intromacro/page2.cml 1. Which of the following elements can be found in all four types…

    • 374 Words
    • 2 Pages
    Decent Essays
  • Improved Essays

    Quiz: Biology

    • 1208 Words
    • 5 Pages

    Big Idea 1: The process of evolution drives the diversity and unit of life. Passage 1: “There are two types of such cells: one is very sensitive to light, the other less so. The more sensitive cells record only in black and white; the less sensitive cells record in color. If we look around the animal world, we can assess whether animals are specialized for daylight or night by looking at the percentages of each type of light-sensing cell in their eyes.” (page 150) Enduring Understanding: 1.A: Change…

    • 1208 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    material. Moreover, this style of interacting learning proved to be overwhelmingly beneficial as it both increased my passion for biology to unprecedented levels and introduced me to the skills of proper laboratory technique that I can use for the rest of my life. I have always enjoyed biology, but in this new learning environment, I was able to thrive. My favorite part of biology is how everything ties together. Organs work together to produce a functioning organism, organisms cooperate to make a population…

    • 709 Words
    • 3 Pages
    Improved Essays