All the three metal mixtures (As + Cd, Cd + Pb and As + Pb) displayed synergistic response at the 10% level and strong synergism was observed for the mixture of As + Pb with CI value of 0.25. The observed synergism was extended up to 30 and 50% level for Cd+ Pb and As + Pb mixtures, respectively. The binary mixture of As + Cd showed an additive response at the 30-50% level. All the mixtures showed an antagonistic effect at the IC90 level and the mixture of As + Pb displayed strong antagonism (CI value 3.3).
4.3.4. Binary mixture toxicity of B[a]P, As, Cd and Pb
The binary mixture of B[a]P + Cd showed a synergistic effect up to the 50% level and antagonism at the 90% level. Mixtures of B[a]P + As, B[a]P + Pb displayed synergism at the 10-30% level, additivity at the 50% level and antagonism at the 90% level. All three mixtures displayed the same levels of synergistic response at lower effect levels (10-30% level).
4.3.5. …show more content…
Ternary and quaternary mixtures toxicity of B[a]P, As, Cd and Pb
Ternary mixtures of B[a]P + As + Cd and B[a]P + Cd + Pb displayed synergism at the 10-50% level and antagonism at the % level. The mixture of B[a]P + As + Pb displayed an antagonistic response for the entire effect level (10-90%). The ternary mixture of As, Cd and Pb showed a synergism at the 10-50% level and an antagonism at the 90% level. Among all the ternary mixtures, metal mixtures showed strong synergism at a lower effect level with a CI value of