Beta blockers are the first line drug choice when treating angina related to CAD. Beta blockers decrease cardiac oxygen demand, by blocking beta receptors in the heart, decreasing heart rate and contractibility, reducing peripheral resistance and after load. Slowing heart rate increases diastolic fill time, increasing the amount of time blood flows throughout myocardial vessels. When taken with nitroglycerin, extra benefits include blunting reflex tachycardia. Dosage starts out low and slowly increases to a therapeutic level. Side effect of blocking beta2 causes bronchoconstriction, while blocking beta1 causes reduction of contractility and bradycardia. Use of specific medications within the class have varying side effects allowing use for those with asthma, COPD and dysrhythmias. Rare central nervous system effects include bizarre dreams, insomnia and depression. (Burcham & Rosenthal, 2016)
HMG-CoA Reductase Inhibitors (Statins) Statins are used to lower LDL cholesterol, elevate HDL cholesterol and reduce triglyceride levels. Life-long treatment is required, due to return to post-treatment levels when the medication is stopped. Statins increase the number of LDL receptor on liver cells by inhibiting hepatic HMG-CoA reductase. This enzyme limits cholesterol biosynthesis. Decrease …show more content…
Primary diseases associated with secondary hypertension include disorders of the renal, endocrine, vascular, neurological disorders; pregnancy-induced hypertension, acute stress and drugs or other substances. Specific diseases or disorders include: renin-producing tumors, renal failure, acromegaly, hyperthyroidism, arteriosclerosis, pregnancy, elevated intracranial pressure, quadriplegia, surgery, burns over 9% or more of the body, alcohol withdrawal, oral contraceptives, antihistamines, licorice and MAOI’s. (McCance, Huether, Brashers & Rote,
HMG-CoA Reductase Inhibitors (Statins) Statins are used to lower LDL cholesterol, elevate HDL cholesterol and reduce triglyceride levels. Life-long treatment is required, due to return to post-treatment levels when the medication is stopped. Statins increase the number of LDL receptor on liver cells by inhibiting hepatic HMG-CoA reductase. This enzyme limits cholesterol biosynthesis. Decrease …show more content…
Primary diseases associated with secondary hypertension include disorders of the renal, endocrine, vascular, neurological disorders; pregnancy-induced hypertension, acute stress and drugs or other substances. Specific diseases or disorders include: renin-producing tumors, renal failure, acromegaly, hyperthyroidism, arteriosclerosis, pregnancy, elevated intracranial pressure, quadriplegia, surgery, burns over 9% or more of the body, alcohol withdrawal, oral contraceptives, antihistamines, licorice and MAOI’s. (McCance, Huether, Brashers & Rote,