A) Benign proliferative breast disease:
1. Fibroadenoma:
Fibroadenoma is the most benign soft tissue mass of the breast and accounts for approximately 40%-50% of all breast biopsies (Liberman, 2000).
Usually it is occurring in patients between the ages of 20-35 years , it increases in size during pregnancy and tends to regress as the age of the patient increases, it is usually single, but in 20% of cases there are multiple lesions in the same breast or bilaterally. Grossly, the usual fibroadenoma is a sharply demarcated, firm mass, usually no more than 3cm in diameter (Rosai, 2004).
Depending on their histological structure fibroadenoma is divided into:
• Pericanalicular fibroadenoma (hard fibroadenoma), it is the common type, which …show more content…
Apocrine adenoma:
A rare form of adenoma composed of apocrine cells (Rosai, 2004).
3. Intraductal papilloma:
Intraductal papilloma of the breast occurs at an average age of 48 years. It can arise in large or small ducts. grossly visible papilloma can present with bloody nipple discharge and may be palpable in a subareolar region , but its diameter rarely exceeds 3cm, a point of importance in the differential diagnosis with papillary carcinoma. Approximately 90% of cases are solitary, while multiple papillomas are seen in slightly younger, arise in smaller ducts, are usually not associated nipple discharge, and are bilateral in one-fourth cases (Rosai, 2004).
4.Nipple adenoma:
It is also known as florid papillomatosis of the nipple. It usually occurs in the fourth or fifth decade, it is a benign lesion that clinically mimics Paget s disease of the nipple. Typically, this lesion present as a discrete, palpably firm tumor of the papilla of the nipple. It is sometimes associated with pruritis and rarely with pain. Often a serous or bloody discharge is noted, and excoriation or ulceration may be noted. Complete excision of the tumor with surgical margins is required for cure. The tumor occupies only