Fibrinolytic Therapy

Fibrinolytic therapy is the most common and widely used reperfusion therapy in patients with a diagnosis of acute ST-segment elevation myocardial infarction (STEMI); it consists of utilizing medications to diffuse the blockage in the infarcted artery. Primary percutaneous coronary intervention (PCI) is an alternate reperfusion therapy which utilizes invasive procedures by the placing stints where the arterial blockage and clot is present. Fibrinolytic therapy has limitations such as; intracranial hemorrhaging, and higher risks of recurrent infarctions or ischemic cardiac events. For PCI to be optimal intervention time from onset of cardiac event is vital. The use and benefits of Percutaneous Interventions (PCI), fibrinolytic or both, to optimize …show more content…
PCI in patients presenting ST-segment elevation myocardial infarction (STEMI) in a pre-hospital setting. The study will further explore each reperfusion therapy as they compare to pre- and post-interventional risks, as well as reduction in both mortality and morbidity rates. An analysis on limitations and accessibility for optimal treatment of patients will be included in the study to compare and contrast each therapy in detail. The effectiveness of each therapy will be further evaluated to facilitate formulating an evidence based medical hypothesis for the preferred interventional …show more content…
The proposal herein addressed will assess data from scholarly peer-reviewed evidence based historical research, which compared the outcomes in fibrinolytic versus PCI. Additionally, a case controlled study will be conducted to include a total of 300 participants, with one-third of the participants presenting a positive STEMI diagnosis. The participants should not exceed 60 years of age, as studies have shown reoccurrence of cardiovascular events after thrombolysis treatment are significantly higher (Danchin et al.,