Avidin-Biotin Interaction that is unfavorable in the human body
Avidin is known to be resistant to pancreatic proteases, therefore there is no absorption of Avidin in the body. Similarly, the binding of Avidin from food sources to dietary Biotin causes no absorption of Avidin-Biotin complex into the body. Biotin will then be carried through the gastrointestinal tract. [2] Decreased Biotin absorption due to Avidin binding leads to Biotin Deficiencies. One well-known Biotin Deficiency is egg white injury which occurs when there is excessive consumption of raw egg whites. Raw egg whites contain glycoprotein Avidin which binds to dietary Biotin, preventing intestinal digestion. Egg white injury results in severe dermatitis, hair loss and neuromuscular
Avidin is known to be resistant to pancreatic proteases, therefore there is no absorption of Avidin in the body. Similarly, the binding of Avidin from food sources to dietary Biotin causes no absorption of Avidin-Biotin complex into the body. Biotin will then be carried through the gastrointestinal tract. [2] Decreased Biotin absorption due to Avidin binding leads to Biotin Deficiencies. One well-known Biotin Deficiency is egg white injury which occurs when there is excessive consumption of raw egg whites. Raw egg whites contain glycoprotein Avidin which binds to dietary Biotin, preventing intestinal digestion. Egg white injury results in severe dermatitis, hair loss and neuromuscular