Autosomal Dominant Polycystic Kidney Disease Essay

1649 Words May 29th, 2016 7 Pages
Autosomal Dominant Polycystic Kidney Disease, also known as ADPKD, is the most commonly inherited kidney disease with over 400,000 US cases per year, Usually an adult-onset disease, ADPKD occurs in individuals and families of different races equally, all over the world. ADPKD causes numerous fluid filled cysts to form in both of the kidneys. As it progresses, the cysts slowly replace most of the normal mass of the kidneys. When this occurs, the cysts often reduce kidney function, which can lead to failure. In most cases, ADPKD takes several years before it causes the kidneys to fail. When this happens, the patient will require either dialysis or a kidney transplant. Around one half of all the people diagnosed with Autosomal Dominant Polycystic Kidney Disease progress to kidney failure, often referred to as end-stage kidney disease, making ADPKD the fourth leading cause of kidney failure in the US. Cysts in those with Autosomal Recessive Polycystic Kidney Disease, ARPKD, can end up spreading to the liver. They may also have develop complications with other organs such as the blood vessels in the brain, and the heart. Both autosomal dominant and recessive Polycystic Kidney Disease require a professional medical diagnosis, including lab tests and imaging. Although ADPKD is present at birth, symptoms often do not appear until the cysts are big enough to start significantly affecting the function of the kidneys, making this an adult-onset disease. In most cases, this doesn’t…

Related Documents