Hereditary Spherocytosis and Autoimmune Hemolytic Anemia
Introduction
Scientifically, hereditary spherocytosis has been known to be a form of an unusual disorder that generically affects a considerable populace around the globe. By definition, hereditary spherocytosis is a term that is accorded to an inherited blood condition that contains abnormally shaped red blood cells (RBCs) (Hsiao et al, 2013). This abnormality has been associated with the reduction of RBCs supply and results into an elevation in the quotient of degeneration same as anemia for patients. On the other hand, autoimmune hemolytic anemia (AIHA) is a condition that destroys a person’s immune system through the destruction of their RBCs. This condition takes effect in a person’s …show more content…
Additionally, these mild symptoms have also been known to be very acute and harsh signs that ascend quickly (Gehrs, Friedberg, 2002). The reasons that may lead to ascend of the signs and symptoms of this health condition have been associated with infections that are their causals ascend. However, the acuteness of this condition may also be detected in children and those people with moderate symptoms may have to wait until their adulthood for detection to be made (Hsiao et al, 2013). In spite of the fact that the signs and symptoms of this condition are mild, a person suffering from this condition is exhibited to have fatigue, jaundice, pallor, gallstones, weakness, hemolytic anemia, shortness of breath as well as irritability and moodiness.
In people who are considered to be healthy, the shape of RBCs is perceived to be as that of a disc that has elevated edges. Nevertheless, people suffering from hereditary spherocytosis have been found to have RBCs shaped like spheres with smaller surfaces that subject them to rupture (Hsiao et al, …show more content…
This has been correlated to the fact that the condition comes as a result of ‘an innate genetic abnormality with the coding used by the body in the production of red blood cells’ (Gehrs, Friedberg, 2002).Nonetheless, this does not mean that the condition cannot be treated. Treatment options that are available for this condition have been known to help patients regulate the signs and symptoms and constitutes of surgery and folic acid supplementation. In the case of surgery, the patient’s spleen is removed as a counter measure to minimize the destruction of the RBCs. Inasmuch as the abnormality of the RBCs may persist, their interference are no longer impaired by the spleen. In the case of folic acid supplementation, the patient is made to take 1 mg folic acid drugs on a daily basis while blood transfusion is recommended. However, this is for patients with ‘acute stages of anemia’ (Gehrs, Friedberg,
Introduction
Scientifically, hereditary spherocytosis has been known to be a form of an unusual disorder that generically affects a considerable populace around the globe. By definition, hereditary spherocytosis is a term that is accorded to an inherited blood condition that contains abnormally shaped red blood cells (RBCs) (Hsiao et al, 2013). This abnormality has been associated with the reduction of RBCs supply and results into an elevation in the quotient of degeneration same as anemia for patients. On the other hand, autoimmune hemolytic anemia (AIHA) is a condition that destroys a person’s immune system through the destruction of their RBCs. This condition takes effect in a person’s …show more content…
Additionally, these mild symptoms have also been known to be very acute and harsh signs that ascend quickly (Gehrs, Friedberg, 2002). The reasons that may lead to ascend of the signs and symptoms of this health condition have been associated with infections that are their causals ascend. However, the acuteness of this condition may also be detected in children and those people with moderate symptoms may have to wait until their adulthood for detection to be made (Hsiao et al, 2013). In spite of the fact that the signs and symptoms of this condition are mild, a person suffering from this condition is exhibited to have fatigue, jaundice, pallor, gallstones, weakness, hemolytic anemia, shortness of breath as well as irritability and moodiness.
In people who are considered to be healthy, the shape of RBCs is perceived to be as that of a disc that has elevated edges. Nevertheless, people suffering from hereditary spherocytosis have been found to have RBCs shaped like spheres with smaller surfaces that subject them to rupture (Hsiao et al, …show more content…
This has been correlated to the fact that the condition comes as a result of ‘an innate genetic abnormality with the coding used by the body in the production of red blood cells’ (Gehrs, Friedberg, 2002).Nonetheless, this does not mean that the condition cannot be treated. Treatment options that are available for this condition have been known to help patients regulate the signs and symptoms and constitutes of surgery and folic acid supplementation. In the case of surgery, the patient’s spleen is removed as a counter measure to minimize the destruction of the RBCs. Inasmuch as the abnormality of the RBCs may persist, their interference are no longer impaired by the spleen. In the case of folic acid supplementation, the patient is made to take 1 mg folic acid drugs on a daily basis while blood transfusion is recommended. However, this is for patients with ‘acute stages of anemia’ (Gehrs, Friedberg,