The adult zebrafish was exposed to graded concentration of atrazine or atrazine degradates such as deisopropylatrazine (DIA), deethylatrazine (DEA) and diamino-s-chlorotriazine (DACT) for up to 10 days. They measured the stress induced cortisol levels of some of the fishes for up to 20 minutes and other fishes were measured for whole body cortisol levels under basal conditions. The results showed that controls not exposed to atrazine and zebrafish exposed to atrazine or the atrazine degradates at nominal concentrations of up to 100 μg/L consistently exhibited increased whole body cortisol content in response to the swimming challenge. Separate analyses revealed few changes in basal or stress induced cortisol levels following atrazine exposure. Overall, these data suggest that atrazine and some of its degradates at the concentrations tested have minimal effects on the cortisol mediated stress response in the zebrafish.This article suggests that, Estrogen-like endocrine disrupting chemicals (EEDC) does not go about as an estrogen mimicker, but instead instigates aromatase
The adult zebrafish was exposed to graded concentration of atrazine or atrazine degradates such as deisopropylatrazine (DIA), deethylatrazine (DEA) and diamino-s-chlorotriazine (DACT) for up to 10 days. They measured the stress induced cortisol levels of some of the fishes for up to 20 minutes and other fishes were measured for whole body cortisol levels under basal conditions. The results showed that controls not exposed to atrazine and zebrafish exposed to atrazine or the atrazine degradates at nominal concentrations of up to 100 μg/L consistently exhibited increased whole body cortisol content in response to the swimming challenge. Separate analyses revealed few changes in basal or stress induced cortisol levels following atrazine exposure. Overall, these data suggest that atrazine and some of its degradates at the concentrations tested have minimal effects on the cortisol mediated stress response in the zebrafish.This article suggests that, Estrogen-like endocrine disrupting chemicals (EEDC) does not go about as an estrogen mimicker, but instead instigates aromatase