On June 23, 1858 a well established Medical Practitioner named Antoine Prosper Marfan and his wife Adelaïde Thuries bought a new life into the world. Antoine Prosper and Adelaide’s son was named Antoine Bernard-Jean Marfan. Bernard’s father, Antoine Prosper had refused to accept his son’s choice in pursuing a career in the medical field. Prosper later gave up on arguing with his son and Bernard went off to study at a medical school in Toulouse, France. Two years went by and Bernard decided to go move to Paris where he took had an internship, however he had to cut it short due to his prior engagement, which was joining the military. Once Bernard was finished with his military service he went to college where he acquired his doctrine and stumbled
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Two primary focal points that makes geneticist classify Marfan as pleiotrophy are their lens and the ligament damage. To tell whether an individual has Marfan Syndrome is based on the dislocation of the lens and deformity of the largest blood vessel connecting to the heart, aorta. The dislocation of the eye lens or a more scientific term is called Ectopia Lentis which causes vision problems. The vision problems that a person may have can cause blurriness resulting in glaucoma and cataracts. The lens of the eye becomes dislocated due to ligaments that provides support making the lens move. Ligaments are a fibrous connective tissue that provides support keeping an organ in a steady position. Dislocation of the lens can be categorized into two different ways. One being, if the supportive ligaments are damaged completely can result in the lens to be out of position is declared as completely detached. Opposite of ‘completely detached’ lens would be a few ligaments being detached and others still holding the organ securely, this is called Partially detached. One aspect of the partially detached lens is that they can be pulled back in place. In addition, the key to identifying the Marfan Syndrome is the defective aorta. The aorta in an individual with Marfan will be relatively weaken and stretched due to the blood vessels connective tissue. The stretching of the aorta can be cause by two highly severe
Two primary focal points that makes geneticist classify Marfan as pleiotrophy are their lens and the ligament damage. To tell whether an individual has Marfan Syndrome is based on the dislocation of the lens and deformity of the largest blood vessel connecting to the heart, aorta. The dislocation of the eye lens or a more scientific term is called Ectopia Lentis which causes vision problems. The vision problems that a person may have can cause blurriness resulting in glaucoma and cataracts. The lens of the eye becomes dislocated due to ligaments that provides support making the lens move. Ligaments are a fibrous connective tissue that provides support keeping an organ in a steady position. Dislocation of the lens can be categorized into two different ways. One being, if the supportive ligaments are damaged completely can result in the lens to be out of position is declared as completely detached. Opposite of ‘completely detached’ lens would be a few ligaments being detached and others still holding the organ securely, this is called Partially detached. One aspect of the partially detached lens is that they can be pulled back in place. In addition, the key to identifying the Marfan Syndrome is the defective aorta. The aorta in an individual with Marfan will be relatively weaken and stretched due to the blood vessels connective tissue. The stretching of the aorta can be cause by two highly severe