Introduction:
An important category of issues in medical science is the diagnosis of diseases, which is based on various tests on the patient. Cancer is the second most common non-accidental cause of mortality in the world. Today, cancer is one of the health problems of the world, and it costs a lot of research every year around the world, this is despite the fact that the third cause of death in our country is "cancer." Unfortunately, the wrong way of life has led to the emergence of cancers as a serious health problem globally, and the rising incidence of infectious diseases is alarming.(1) Lowering the Age The prevalence of some cancers, including breast cancer, in young girls and young women is another dilemma that health and research …show more content…
Also, miR-21 expression is very high in radiation-resistant cells, but does not change in radioactive-sensitive cells.Also, miR-21 expression is very high in radiation-resistant cells, but does not change in radioactive-sensitive cells;Therefore, the expression of miR-21 has no relation to oncogenesis, but acts as a resistant miRNA. The miR-155 is one of the biomarkers that is directly linked to the progression of tumors in a variety of cancers, including breast cancer, and is constantly increasing. Clinical data suggest that miR-155 has a major function in the prognosis, diagnosis and progression of the tumor, and also causes metastasis. These miRNAs contribute to the progression of breast cancer, induction of tumorigenicity and enrichment of the cancerous stem cell phenotype, as well as resistance to tumor-related therapeutic components. Which has the highest expression in postoperative wound fluids )WFs(; Recent research studies have shown that the intraoperative radiotherapy (IORT) method of regulating miR-155 and miR-21 significantly.(16) Dependent on the observation miR-373 is overexpressed in breast cancer lymph node metastases, circulating ranges of miR-373 was assessed in the sera for their prospective utilization as biomarker for detecting breast cancer lymph node metastases.(17) Let-7b has been proven to be decreased in numerous kinds of tumor tissues such as breast cancer.Let-7b serves as a tumor suppressor by focusing on numerous oncogenic pathways in cancer cells. For instance, let-7b is concerned in cell motility, cell cycle progression and cell division by way of regulating a series of related genes, such as PAK1, DIAPH2, CDK6 and CDC25.(17) The human miR-34 family consists of miR-34a, miR-34b, and miR-34c. The miR-34 miRNAs are tumor suppressors and are vital mediators in the p53 pathway. In specific, it has been proven that the miR-34 family members decrease cell
An important category of issues in medical science is the diagnosis of diseases, which is based on various tests on the patient. Cancer is the second most common non-accidental cause of mortality in the world. Today, cancer is one of the health problems of the world, and it costs a lot of research every year around the world, this is despite the fact that the third cause of death in our country is "cancer." Unfortunately, the wrong way of life has led to the emergence of cancers as a serious health problem globally, and the rising incidence of infectious diseases is alarming.(1) Lowering the Age The prevalence of some cancers, including breast cancer, in young girls and young women is another dilemma that health and research …show more content…
Also, miR-21 expression is very high in radiation-resistant cells, but does not change in radioactive-sensitive cells.Also, miR-21 expression is very high in radiation-resistant cells, but does not change in radioactive-sensitive cells;Therefore, the expression of miR-21 has no relation to oncogenesis, but acts as a resistant miRNA. The miR-155 is one of the biomarkers that is directly linked to the progression of tumors in a variety of cancers, including breast cancer, and is constantly increasing. Clinical data suggest that miR-155 has a major function in the prognosis, diagnosis and progression of the tumor, and also causes metastasis. These miRNAs contribute to the progression of breast cancer, induction of tumorigenicity and enrichment of the cancerous stem cell phenotype, as well as resistance to tumor-related therapeutic components. Which has the highest expression in postoperative wound fluids )WFs(; Recent research studies have shown that the intraoperative radiotherapy (IORT) method of regulating miR-155 and miR-21 significantly.(16) Dependent on the observation miR-373 is overexpressed in breast cancer lymph node metastases, circulating ranges of miR-373 was assessed in the sera for their prospective utilization as biomarker for detecting breast cancer lymph node metastases.(17) Let-7b has been proven to be decreased in numerous kinds of tumor tissues such as breast cancer.Let-7b serves as a tumor suppressor by focusing on numerous oncogenic pathways in cancer cells. For instance, let-7b is concerned in cell motility, cell cycle progression and cell division by way of regulating a series of related genes, such as PAK1, DIAPH2, CDK6 and CDC25.(17) The human miR-34 family consists of miR-34a, miR-34b, and miR-34c. The miR-34 miRNAs are tumor suppressors and are vital mediators in the p53 pathway. In specific, it has been proven that the miR-34 family members decrease cell