With this work, it has been possible to demonstrate that the three mitochondrial AtAPCs in Arabidopsis are capable of transporting phosphate, AMP, ADP, ATP, adenosine 5'-phosphosulfate and, to a lesser extent, other nucleotides. Additionally AtAPC2 and AtAPC3 also have the ability to transport sulfate and thiosulfate. Given that mitochondria already possess specific transporters for phosphate and sulfate, it is presumable that the AtAPCs transport activity is involved in the net influx of adenine nucleotides in those conditions where the concentrations of adenine nucleotides limit mitochondrial biosynthesis. The data presented here also reveals that the mitochondrial AtAPCs are regulated at the transcriptional level and by Ca2+,
With this work, it has been possible to demonstrate that the three mitochondrial AtAPCs in Arabidopsis are capable of transporting phosphate, AMP, ADP, ATP, adenosine 5'-phosphosulfate and, to a lesser extent, other nucleotides. Additionally AtAPC2 and AtAPC3 also have the ability to transport sulfate and thiosulfate. Given that mitochondria already possess specific transporters for phosphate and sulfate, it is presumable that the AtAPCs transport activity is involved in the net influx of adenine nucleotides in those conditions where the concentrations of adenine nucleotides limit mitochondrial biosynthesis. The data presented here also reveals that the mitochondrial AtAPCs are regulated at the transcriptional level and by Ca2+,