It would be impossible to make a direct comparison of the four studies critiqued due to the differing methods and study designs; however, it provides a good foundation to determine if the use of apneic oxygenation should be considered in standard practice. In research conducted by Miguel-Montanes and colleagues (2015) and Sakles and colleagues (2016), use of apneic oxygenation was found to decrease the incidence of oxygen desaturation during intubation when compared to a non-rebreather mask for pre-oxygenation alone. These were both single-center observational studies conducted at teaching hospitals. Despite the study designs, diversity of the patient populations studied, and the different settings, increase the likelihood that apneic oxygenation
