Antithrombotic Therapy And Prevention Of Thhrombosis Case Study

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The recommendations in the guideline The Antithrombotic Therapy and Prevention of Thrombosis, 9th Ed: American College of Chest Physicians Evidence-Based Clinical Practice do have a level/strength of evidence upon them. Recommendations were formulated between “a balance between the desirable and undesirable consequences of an intervention; the quality of evidence; the variability in patient values and preferences; and, on occasion, resource use issues.” Recommendations were graded as strong for desirable effects and weak for undesirable effects. Stronger effects were worded as, “The expert panel recommends”, and the weak effects were worded as, “The expert panel suggests.” The quality of evidence was graded by the letter A being the highest, and letter C being the lowest. The formulated recommendations are appropriate for this guideline. The final recommendations were critiqued and any consensus about the article was discussed at a final conference by a …show more content…
The guideline stated that, “for patients undergoing major orthopedic surgery (THA, TKA, HFS) and receiving LMWH as a thromboprophylaxis, the expert panel recommends starting either 12 hours or more preoperatively or 12 hours or more postoperatively rather than within 4 hours or less preoperatively or 4 hours less postoperatively (Grade 1 B).” (American College of Chest Physicians)

4.) The recommendation that is the most useful for Megan’s medical-surgical population would be, “the use of LMWH, fondaparinux, apixaban, dabigatran, rivaroxaban, low-dose unfractionated heparin,adjusted-dose vitamin K antagonist, aspirin, or an IPCD for a minimum of 10 to 14 days undergoing Total Hip Arthroplasty, Total Knee Arthroplasty or the use of LMWH, fondaparinux, LDUH, adjusted-dose VKA, aspirin, or an IPCD for a minimum of 10 to 14 days undergoing Hip Fracture surgery.”(American College of Chest

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