The heretical concept of antimicrobial resistance:
In mid 1950 which is known to be one of the most significant year of Medical science when genetically transferred antibiotic resistance was identified in Japan and a theory has established on the basis of scientific data is that during Bacterial conjugation resistance genes or r genes are propagated from one strain to an entire population. Therefore Bacterial Genome evolution has started taking place as one of the major fields in Microbiology, that deals with the importance of horizontal gene transfer(HGT) and its several other aspects in terms of promoting pathogenicity and resistance against antibiotic. Most recently, plasmid mediated antibiotic resistance has become one of the major focus of investigation because of its practical relevance(6-Norman, A., L. H. Hansen, and S. J. Sorensen. 2009. Conjugative plasmids: vessels of the communal gene pool. Philos. Trans. R. Soc. Lond. B. …show more content…
The aim of this study was to identify the class-Ι, ΙΙ, ΙΙΙ integration and its role in mediating multidrug resistance. They used Multiplex PCR technique as a basis of experimental approach to analyze the individual segments of integron. At the beginning of this experiment, Staph.aureus strains were identified and then cultured out from sutum,blood,cerebrospinal fluid,cxcretion fluid, and urine specimen of affected individuals.The range of antibiotic sensitivity of these SA strains isolated from specimen was measured by using 20 different types of antibiotics. Therefore, three distinct antibiotics were appeared to become highly resistant in SA strain, those were benzylpenicillin(93.7%), erythromycin(81.1%), and azithomycin (79.4%), whereas, three antibiotics with the lowest resistance rate in SA strain were Vancomycin(0%), teicoplanin(2.2),
In mid 1950 which is known to be one of the most significant year of Medical science when genetically transferred antibiotic resistance was identified in Japan and a theory has established on the basis of scientific data is that during Bacterial conjugation resistance genes or r genes are propagated from one strain to an entire population. Therefore Bacterial Genome evolution has started taking place as one of the major fields in Microbiology, that deals with the importance of horizontal gene transfer(HGT) and its several other aspects in terms of promoting pathogenicity and resistance against antibiotic. Most recently, plasmid mediated antibiotic resistance has become one of the major focus of investigation because of its practical relevance(6-Norman, A., L. H. Hansen, and S. J. Sorensen. 2009. Conjugative plasmids: vessels of the communal gene pool. Philos. Trans. R. Soc. Lond. B. …show more content…
The aim of this study was to identify the class-Ι, ΙΙ, ΙΙΙ integration and its role in mediating multidrug resistance. They used Multiplex PCR technique as a basis of experimental approach to analyze the individual segments of integron. At the beginning of this experiment, Staph.aureus strains were identified and then cultured out from sutum,blood,cerebrospinal fluid,cxcretion fluid, and urine specimen of affected individuals.The range of antibiotic sensitivity of these SA strains isolated from specimen was measured by using 20 different types of antibiotics. Therefore, three distinct antibiotics were appeared to become highly resistant in SA strain, those were benzylpenicillin(93.7%), erythromycin(81.1%), and azithomycin (79.4%), whereas, three antibiotics with the lowest resistance rate in SA strain were Vancomycin(0%), teicoplanin(2.2),