Antibiotic Sensitivity Testing ( Mdr Tb ) Essay

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Introduction:

Antibiotic sensitivity testing is used in clinical laboratories to predict the effectiveness or failure of antibiotics in vivo by testing in vitro. The need for antibiotic sensitivity testing is urgent due to the surge of antimicrobial resistant pathogens in recent years. Antimicrobial resistance hinders the prevention and treatment of the infections caused by parasites, bacteria, fungi and viruses. Antimicrobial resistance is the resistance of a pathogen to an antimicrobial that was used to treat any infections caused by that particular pathogen. Antimicrobial resistance is a global problem. Antibiotic resistance hampers the effectiveness of treatments, so people remain infected for much longer therefore increasing the risk of the spread of the antimicrobial resistant pathogen to others. Some antimicrobial resistant pathogens include methillin-resistant Staphylococcus aureus (MRSA) and multi-drug resistant TB (MDR-TB). Antimicrobial resistance is mainly caused by the overuse of antibiotics, so the pathogens encounter these antibiotics and they then evolve and overcome the antibiotic that was prescribed to treat it. The pathogen overcomes the antibiotic by an increase in its minimum inhibitory concentration (MIC), the MIC is the minimum concentration of antibiotic required to kill a microbe.
The increased usage and unnecessary prescription of antibiotics leads to increased antibiotic resistance. This is where antibiotic sensitivity testing comes into play.…

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