Another method in which antibiotic resistance occurs is via the freezing of polymorphisms (Eric
D. Brown and Gerald D. Wright 2016). Polymorphisms are discontinuous variations in gene which results in numerous types of individuals within a species an example being the variations that exist between the single Canisfamiliaris species of dog. In the case of antibiotic resistance, freezing of certain polymorphisms means that bacte1ia cells who have variation which adequate makes up for fitness declines, which arise from resistance genes, will smvive and these polymorphisms freeze and become the standard variation for the next generation of bacte1ia. Resulting in a new generation of drug resistant bacteria that function at an efficient fitness. …show more content…
P. & Chain, E. 1940). Such processes of resistance pose problems for the community, applying pressure for new era of medication, made with the advances in computation and biochemical engineering techniques that can treat the pathogens that are once again able to infect and harm society without control.
One of the ways scientists are looking to solve antibiotic resistance is to examine synthetic viability of gene interactions. Synthetic viability is where a bacterial strain which would not viable in normal high nutrients culture condition after antibiotic treatment, remains viable in certain specific conditions (deletion of anti-toxin gene has no effect on bacteria cell in a
11
non-toxic environment) (Gerdes, K., Christensen, S. K. & L0bner-Olesen , A. (2005)). As such
there is a focus on examining the effects of antibiotic on bacteria which exist in vivo to better identify possible antibiotic targets. Building on this focus for research in combination effects, is examination of the relationshi p between antibiotics and other molecules, building on the pretense that one molecule can enhance the effect of another. For exam ple multiple molecules were found to increase the permeability and cell shape of gram negative E-coli (Dylor, P. L., Rossi, L.,
D. Brown and Gerald D. Wright 2016). Polymorphisms are discontinuous variations in gene which results in numerous types of individuals within a species an example being the variations that exist between the single Canisfamiliaris species of dog. In the case of antibiotic resistance, freezing of certain polymorphisms means that bacte1ia cells who have variation which adequate makes up for fitness declines, which arise from resistance genes, will smvive and these polymorphisms freeze and become the standard variation for the next generation of bacte1ia. Resulting in a new generation of drug resistant bacteria that function at an efficient fitness. …show more content…
P. & Chain, E. 1940). Such processes of resistance pose problems for the community, applying pressure for new era of medication, made with the advances in computation and biochemical engineering techniques that can treat the pathogens that are once again able to infect and harm society without control.
One of the ways scientists are looking to solve antibiotic resistance is to examine synthetic viability of gene interactions. Synthetic viability is where a bacterial strain which would not viable in normal high nutrients culture condition after antibiotic treatment, remains viable in certain specific conditions (deletion of anti-toxin gene has no effect on bacteria cell in a
11
non-toxic environment) (Gerdes, K., Christensen, S. K. & L0bner-Olesen , A. (2005)). As such
there is a focus on examining the effects of antibiotic on bacteria which exist in vivo to better identify possible antibiotic targets. Building on this focus for research in combination effects, is examination of the relationshi p between antibiotics and other molecules, building on the pretense that one molecule can enhance the effect of another. For exam ple multiple molecules were found to increase the permeability and cell shape of gram negative E-coli (Dylor, P. L., Rossi, L.,