The composition of an antacid includes a basic chemical compound (the active ingredient), which is an essential component of a neutralization reaction. When this compound along with an acidic compound (HCl) dissociates, it reacts and forms neutralized components such as water and a salt. This is an ideal mechanism of action for individuals who suffer from acid reflux or heartburn conditions, because the presence of excessive HCl in the stomach can be alleviated by ingesting antacid tablets. This experiment explored the effectiveness of different antacids base on the number of HCl moles neutralized by the antacid. The data favored Alkalac as the most effective antacids base on moles neutralized per dosage (0.0134 moles of HCl).
Introduction …show more content…
The stopcock of the burette filled with 0.25 M NaOH was carefully opened, allowing drips of NaOH into the hydrochloric acid stock solution with the immersed magnetic stir bar. Once the hydrochloric acid stock solution turned into a pale pink color, the stopcock of the burette was immediately closed. Determination of the amount of NaOH utilized was calculated by taking the difference of the final and initial volume, which was then recorded (depicted in Table 1). These steps were performed four times for the additional prepared 20 mL solution in the separate beakers.
Results
The data obtained for the amount of NaOH used to achieve a pale pink coloration of the hydrochloric acid stock is depicted in Table 1 and the amount of moles neutralized is provided in Table 2. In order to calculate the amount of moles neutralized, the average of the 3 closest trials were calculated and recorded. This was achieved by adding up the total volumes of the 3 closest trials and dividing the sum by 3, which resulted in an average of 1.27 mL. Provided below are the additional calculations computed to obtain the moles of HCl …show more content…
The active ingredient/chemical compound present in the involved antacids Medi-first, Gelusil, Acalak and Alka-Seltzer are listed respectively: calcium carbonate, aluminum hydroxide/magnesium hydroxide, calcium carbonate and sodium bicarbonate [1]. The effectiveness of each antacid listed above was tested and calculated in the same manner. Phenolphthalein indicator was used because of its ability to express the pH range of the solution during the acidic (colorless) and basic (pink) phase in the course of the experiment. NaOH is in fact a basic chemical compound used in this experiment, however, its value was not included in the total moles neutralized and for that reason it was subtracted to reflect the moles neutralized by just the
Introduction …show more content…
The stopcock of the burette filled with 0.25 M NaOH was carefully opened, allowing drips of NaOH into the hydrochloric acid stock solution with the immersed magnetic stir bar. Once the hydrochloric acid stock solution turned into a pale pink color, the stopcock of the burette was immediately closed. Determination of the amount of NaOH utilized was calculated by taking the difference of the final and initial volume, which was then recorded (depicted in Table 1). These steps were performed four times for the additional prepared 20 mL solution in the separate beakers.
Results
The data obtained for the amount of NaOH used to achieve a pale pink coloration of the hydrochloric acid stock is depicted in Table 1 and the amount of moles neutralized is provided in Table 2. In order to calculate the amount of moles neutralized, the average of the 3 closest trials were calculated and recorded. This was achieved by adding up the total volumes of the 3 closest trials and dividing the sum by 3, which resulted in an average of 1.27 mL. Provided below are the additional calculations computed to obtain the moles of HCl …show more content…
The active ingredient/chemical compound present in the involved antacids Medi-first, Gelusil, Acalak and Alka-Seltzer are listed respectively: calcium carbonate, aluminum hydroxide/magnesium hydroxide, calcium carbonate and sodium bicarbonate [1]. The effectiveness of each antacid listed above was tested and calculated in the same manner. Phenolphthalein indicator was used because of its ability to express the pH range of the solution during the acidic (colorless) and basic (pink) phase in the course of the experiment. NaOH is in fact a basic chemical compound used in this experiment, however, its value was not included in the total moles neutralized and for that reason it was subtracted to reflect the moles neutralized by just the