Abstract
Adenoidectomy is a very common operation in children. Uncontrolled bleeding increases duration of operation, risk of infection, possibility of blood transfusion, cost of care and morbidity/mortality rates. This is of high importance especially in young children where normal physiological mechanisms are less adaptable to a rapid blood loss. This study was planned to investigate the safety and efficacy of two topical hemostatic modulators; Ankaferd Blood Stopper (ABS) and Feracrylum 1% solution (FS) to during adenoid surgery in infants. Two hundred and twenty-five consecutive pediatric adenoid patients aged from 9 months to 2 years old were studied. Patients were randomly allocated to 3 hemostatic groups; ABS, FS and physiological normal …show more content…
Topical hemostatic agents are now frequently used in surgical and trauma sites. Ankaferd blood stopper (ABS) is a hemostatic agent composed of plant extracts, specifically Urtica dioca (0.06 mg/ml),Vitis vinifera (0.08 mg/ml), Glycyrrhiza glabra (0.07 mg/ml), Alpinia vinifera officinarum (0.07 mg/ml) and Thymus vulgaris (0.05 mg/ml). Each of these constituents has some effect on the endothelium, blood cells, angiogenesis, cellular proliferations, vascular dynamics, and cell mediators [12]. Feracrylum is a water-soluble mixture of incomplete ferrous salt of polyacrylic acid containing 0.05 to 0.5% of iron in combination with the pharmaceutical solvent which is water or physiologic solution. Feracrylum is obtained by polymerization of acrylic acid inhibited by redox- system in aqueous medium at 50°C temperature [13]. Understanding how and when to use each of the available hemostatic agents can greatly affect clinical outcomes and help in reducing morbidities and mortalities as well as limiting the overall cost of treatment [14]. Therefore, this study was planned in a prospective randomized controlled fashion to investigate the safety and efficacy of two topical hemostatic modulators; ABS and FS, to control bleeding during adenoid surgery in
Adenoidectomy is a very common operation in children. Uncontrolled bleeding increases duration of operation, risk of infection, possibility of blood transfusion, cost of care and morbidity/mortality rates. This is of high importance especially in young children where normal physiological mechanisms are less adaptable to a rapid blood loss. This study was planned to investigate the safety and efficacy of two topical hemostatic modulators; Ankaferd Blood Stopper (ABS) and Feracrylum 1% solution (FS) to during adenoid surgery in infants. Two hundred and twenty-five consecutive pediatric adenoid patients aged from 9 months to 2 years old were studied. Patients were randomly allocated to 3 hemostatic groups; ABS, FS and physiological normal …show more content…
Topical hemostatic agents are now frequently used in surgical and trauma sites. Ankaferd blood stopper (ABS) is a hemostatic agent composed of plant extracts, specifically Urtica dioca (0.06 mg/ml),Vitis vinifera (0.08 mg/ml), Glycyrrhiza glabra (0.07 mg/ml), Alpinia vinifera officinarum (0.07 mg/ml) and Thymus vulgaris (0.05 mg/ml). Each of these constituents has some effect on the endothelium, blood cells, angiogenesis, cellular proliferations, vascular dynamics, and cell mediators [12]. Feracrylum is a water-soluble mixture of incomplete ferrous salt of polyacrylic acid containing 0.05 to 0.5% of iron in combination with the pharmaceutical solvent which is water or physiologic solution. Feracrylum is obtained by polymerization of acrylic acid inhibited by redox- system in aqueous medium at 50°C temperature [13]. Understanding how and when to use each of the available hemostatic agents can greatly affect clinical outcomes and help in reducing morbidities and mortalities as well as limiting the overall cost of treatment [14]. Therefore, this study was planned in a prospective randomized controlled fashion to investigate the safety and efficacy of two topical hemostatic modulators; ABS and FS, to control bleeding during adenoid surgery in