Analyzing The Design, Synthesis, And Test Of The E. Coli 57 Codon Genome

763 Words Oct 17th, 2016 4 Pages
Since the beginning of time, genomes have been in existence since the -, “so-called big bang theory”. Genomes are the key to life because they are an organism’s complete set of deoxyribonucleic acid (DNA). DNA is the source in which processes transcription takes place to form a ribonucleic acid (RNA) and is then translated into an amino acid, which is the essential building block of protein to life. For example, hemoglobin, the cells in our bone marrow, churn out a hundred trillion per second of hemoglobin, which is a red protein responsible for transporting oxygen in the blood of the vertebrates. Life consists of genomes, which contain all the information to build and support an organism. Rewriting genomes can eventually affect and change an organism 's genome and phenome. In this article review, we will be reviewing the design, synthesis, and test of the E. coli 57-codon.
In this specific study, done by Ostrov and many others about the synthesis of a 57-codon genome, the scientists used other studies done in 2009, 2010, and 2013 to improve on this research and have created a software that would help find suitable replacements for the genome-codon recoding process in a prokaryotic genome, single-chromosome organelle. Researchers in this experiment were trying to simplify the genome, as well as elongate the sequence. For protein synthesis to happen ribosomes move along the mRNA, reads each codon, takes the tRNA, the factor that elongates the protein Tu (EF-Tu), and guanosine…

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