There were several issues in the collision of the two worlds. The first of the issues was the struggle for land. The Spanish who first came to America took land from the Indians. They were in the search for gold and in order to get it they felt they had to take the land it was in. This led to the struggle between both parties for land. Another issue was Disease. The Indians were more wiped out by disease than they were combat. They did not have an immune system that would fight off the diseases that was brought over by the Europeans. Another issue was the way that the Indians were treated. They were treated as subhuman. Away from the warfare, the men could still be killed, and the children and women could be taken as slaves to help the European
