Analysis Of Duchenne Muscular Dystrophy ( Dmd ) Essay

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Duchenne Muscular Dystrophy (DMD) is named after the French neurologist Guillaume Benjamin Amand Duchenne who first described the disease. It is one of nine types of muscular dystrophy. Muscular dystrophy is characterized by progressive muscle degeneration (Muscular Dystrophy Association). Muscle weakness appears in early childhood and progressively worsens; children with DMD are generally wheel-chair dependent by adolescence. Along with the DMD affecting the skeletal system, the cardiac muscles are also affected and result in cardiomyopathy. Cardiomyopathy is a heart disease where weak cardiac muscle prevents the heart from pumping blood efficiently. Typically, males with DMD live into their twenties before the cardiac muscles can no longer function (Genetics Home Reference). DMD is a Mendelian, or due to a single gene, X-linked recessive disorder that causes a lack of the protein dystrophin because of a mutation. As a result of lack of dystrophin, muscle cells become extremely fragile. According to the CDC, Duchenne Muscular Dystrophy is prevalent in an estimated 1-3,500 male and is almost exclusive in males. DMD is not specific to any one ethnic group. However, according to a 2015 study by the American Academy of Pediatrics, it was found that the prevalence of the disorder in the Hispanic population was greater than non-Hispanic white or black individuals but not limited to those populations. Since Duchenne Muscular Dystrophy is a genetic disease, the first step of…

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