Alzheimer’s disease (AD) is the most common cause for dementia, afflicting about 5% of the population older than 65 years (Alloul et al., 1998, as cited, Maia and Medonca, 2002). It is a genetic disease caused by a mutation of the amyloid precursor protein (APP) gene. This type of gene is mostly found in the central nervous system which it helps direct migration of neurons during early development (Genetics Home Reference). Linn and Small stated that there is evidence that Alzheimer’s can be diagnosed by a long pre-clinical phase (as cited in Maia and Mendoca, 2002). A case-study predicted that caffeine might have a genuine protective effect on the pathogenic changes of Alzheimer’s disease (Maia and Medonca, 2002). In this study, 54 patients
