Alzheimer’s disease (AD), was discovered as senile form of dementia in early 1907 by Alois Alzheimer in 1907. Since then the disease has been researched and studied to generate a knowledge base of symptoms, etiology, pathogenesis, treatment and management of the disease. AD is differentiated from senile dementia due to the neurodegenerative process which involves deposits of protein known as amyloid in neurons and neurofibrillary tangles which form plaques. This formation of plaques leads to neuron death and the hardening of tissue leads to progressive and terminal neurological disease state. There has been no cure to Alzheimer’s disease to the complexity of disease and the lack of understanding of amyloid protein and its process. Mild cognitive
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• Anti-plaque formation treatment using monoclonal antibody Anti- Aβ 42 AB, such as Crenezumab, Solanzezumab and Bapinezumab.
• Monoclonal Ab or gene therapy to target APOE-4 variant, treatment that mimics APP gene that confers protection against AD.
• Antioxidant therapy to tackle oxidative stress.
Professionals in healthcare system that treat patients with AD.
According to Shan.Y (2013), Psychiatrists, clinical psychologists, neurologists, community nurses, mental health nurses, home health assistants, social services, police and community outreach are few professionals that provide services to patients with AD (p.37).
Complications of AD: Complications of AD are secondary to the neurodegenerative and terminal process of the disease. Death occurs in patients with AD due to secondary infections and immune processes. Cerebrovascular accidents such as strokes are causative process that lead to death in AD, also infections such as pneumonia and sepsis.
List of providers that treat AD in the area:
City of Cleveland
Thomas Gretter,
• Anti-plaque formation treatment using monoclonal antibody Anti- Aβ 42 AB, such as Crenezumab, Solanzezumab and Bapinezumab.
• Monoclonal Ab or gene therapy to target APOE-4 variant, treatment that mimics APP gene that confers protection against AD.
• Antioxidant therapy to tackle oxidative stress.
Professionals in healthcare system that treat patients with AD.
According to Shan.Y (2013), Psychiatrists, clinical psychologists, neurologists, community nurses, mental health nurses, home health assistants, social services, police and community outreach are few professionals that provide services to patients with AD (p.37).
Complications of AD: Complications of AD are secondary to the neurodegenerative and terminal process of the disease. Death occurs in patients with AD due to secondary infections and immune processes. Cerebrovascular accidents such as strokes are causative process that lead to death in AD, also infections such as pneumonia and sepsis.
List of providers that treat AD in the area:
City of Cleveland
Thomas Gretter,