Alzheimer 's Disease : A Disease Of The Brain Essay

1374 Words Jul 18th, 2016 6 Pages
Alzheimer’s disease is a disease of the brain that causes problems with memory, thinking and behavior. This disease develops over a number of years and symptoms progress with time. It was first recognized by Alois Alzheimer, a German doctor, in 1906 after he discovered variations in the brain tissue of a woman who had died of an uncommon mental illness. (“Alzheimer’s Disease”). At the time that it was first documented, it was thought to be a rare disease. Dr. Alzheimer found many amyloid plaques and neurofibrillary tangles in her brain upon investigation (“Alzheimer’s Disease Fact Sheet”). Currently, Alzheimer’s is the most common form of dementia, and it accounts for 60-80 percent of dementia cases.
There is a current belief that damage to the brain begins about 10 or more years before symptoms of Alzheimer’s disease appear. Although individuals do not typically have any symptoms at this point in time, there are still toxic modifications that are occurring in the brain (“Alzheimer’s Disease Fact Sheet”). The damage originally takes place in the hippocampus which is the part of the brain that is responsible for the formation of memories.
There are three parts of the brain that are mainly affected by this disease. These include amyloid plaques, neurofibrillary tangles and the loss of connections between the neurons responsible for memory and learning abilities (“NINDS”). In those with Alzheimer’s amyloid plaques interfere with the communication between different cells which…

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