Alpha-Actinin-3 Protein Synthesis

Improved Essays
Genes act as codes to produce proteins, which can affect a person’s athletic ability. According to research, an athlete’s genes can influence 20-80% of their performance.
Athletic performance has a significant association with ACTN-3 genotype. It produces the protein α-actinin-3 that is found in in fast-twitch muscle fibres which are responsible for generating force for high-velocity movement. Yang et al. hypothesize that α-actinin-3 can influence sprint and power activities by “promoting fast-twitch muscle fiber formation or changing the glucose metabolism during athletic training.” α-actinin-3 may promote the “absorption or transmission of force during muscle contraction,” resulting in less damage.
Their research has shown that the R and X allele of ACTN-3 have an impact in athleticism. According to their research, the XX genotype is more frequent in endurance athletes while the RR genotype is more frequent in power athletes. The R allele produces a lot of the α-actinin-3 protein and the X allele puts a premature stop to the growing protein chain resulting in a non-functional α-actinin-3 protein. α-actinin-3 is not necessary in normal muscle function, but it is associated with muscle strength. The X allele, on the other hand, can give an advantage on slow, efficient muscle performance, which may make it enhance endurance performance. The data from their study showed that more endurance athletes have the XX genotype is more endurance athletes have the XX genotype, indicating that the X allele may have an enhancing effect on endurance.
…show more content…
The XX genotype is more frequent in endurance athletes than power athletes and controls. The RR genotype is most frequent in power athletes compared to endurance athletes and

Related Documents

  • Improved Essays

    1. Although the role of genes plays a factor in athletic performance, the process of translating it to the actual playing field is a lot more difficult and important. For this reason, I do believe that sports are fair. In Farrey’s argument, he points out studies that showed that genes appear to deserve credit for about two-thirds of vertical leaping ability and that balance and flexibility are at least somewhat inherited.…

    • 1218 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    In, The Sports Gene, Epstein shows how genes may have had an impact on two high-jumper's talents. "Thomas's long legs relative to his height and also that he was gifted with a giant's Achilles tendon" (Epstein 15). Epstein shows that Thomas may have an advantage over other high-jumpers that practice a lot because of his gifted Achilles tendon. Also,…

    • 441 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    In the text of the Sports Gene, Thomas is gifted with a “giants Achilles tendon.” The longer the Achilles tendon, the higher your jump will be. Genes determine certain things…

    • 303 Words
    • 2 Pages
    Improved Essays
  • Decent Essays

    Belgian Blue bulls have extremely large muscles in the shoulder, back, loin and rump area. This extreme growth in muscle is due to a mutation in the myostatin gene, which results in the production of increased number of muscle fibers (hyperplasia). Breeders choose the cattle that clearly demonstrate the myostation defect. They choose the cattle that has the most muscle mass so they can gain the best out of their offspring. By doing so they also eliminate the undesirable characteristics in the species.…

    • 244 Words
    • 1 Pages
    Decent Essays
  • Great Essays

    Genetics play a major and often pivotal role in athletic excellence. Stefan Holm lived for the high jump. Holm spent much of his early life perfecting his high jumping form including dropping out of school to train. Holm’s success was great and he won the Olympic title in 2005 equaling the record of the highest high jump with 7’10.5 (Epstein 27).…

    • 1570 Words
    • 7 Pages
    Great Essays
  • Superior Essays

    Nature vs Nurture Are criminals born or made? Are the way that someone is brought up the way they are supposed to be? Are people who have distinct genetics the ones that are definite criminals? Nature vs Nurture is a debate that has been going on for many years, The question is is a person genetically made up to be bad or is it the environment that they are exposed to the thing that change them.…

    • 2066 Words
    • 9 Pages
    Superior Essays
  • Superior Essays

    The purpose of this experiment was to examine the difference between slow and fast twitch muscle fibers between men and women. Based on the definitions of slow and fast twitch muscle fibers, and given the fact that previous studies state that testosterone increases fast twitch muscle fibers, we expect that athletic men will have a higher leap because they have more fast twitch muscle fibers.…

    • 2096 Words
    • 9 Pages
    Superior Essays
  • Improved Essays

    Imaging Vs Ultrasound

    • 986 Words
    • 4 Pages

    Advancement of medical imaging modalities, such as ultrasound, has significantly helped researchers and health professionals visualise dimensional and morphologic changes within the tendon, such as may occur with overuse injuries amongst athletes. Both Magnetic Resonance Imaging (MRI) and ultrasound have unique benefits and limitations. MRI may be better suited where there is a need for a differential diagnosis while ultrasound can be used to demonstrate active and passive movements in real time. Ultrasound is more portable and has greater accessibility and affordability over MRI however, ultrasound is more operator dependent [5]. There is little research that have made a direct comparison between ultrasound and MRI, however a study investigating…

    • 986 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Wingate Test Analysis

    • 803 Words
    • 4 Pages

    The ATP-PCr will be an essential pathway to assist the muscle actions of the legs, to increase and generate more force in the performance to produce higher values in mean values in capacity and relatively. 4. Was there a drop-off in anaerobic power during the Wingate Test? Why?…

    • 803 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Blood Doping Research Paper

    • 2523 Words
    • 11 Pages

    Introduction A common form of athletic enhancement for athletes who compete in marathons or cycling is known as blood doping. Jeanna Bryner, Managing Editor of Live Science, states it is “an illicit method of improving athletic performance by artificially boosting the blood 's ability to bring more oxygen to muscles.” Marathonist and cyclists use this method over steroids because if there is more oxygen going into their muscles, then they are able to increase their stamina and performance. This increase allows athletes to travel long distances without becoming fatigued.…

    • 2523 Words
    • 11 Pages
    Improved Essays
  • Improved Essays

    A. M. (n.d.). Genetically Modified Athletes; Biomedical ethics, gene doping and sport. Retrieved from http://samples.sainsburysebooks.co.uk/9781134425990_sample_535540.pdf This source is a primary source (book) written by a scientist named Andy Miah. This book focused on the bioethics of this current issue and went into details about the applications for the genetically modified athlete. This source is important because it gives the bioethics stance on this issue.…

    • 1218 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    Eukaryotic Synthesis

    • 1359 Words
    • 6 Pages

    As described in the central dogma of biology, information from a gene can be used to build a protein in a two-step process. Transcription is considered to be the first step of gene expression. It is known to be the process of making a copy of genetic information stored in a DNA strand into a complementary strand of messenger RNA (mRNA). The process of eukaryotic transcription can be separated into three phases, initiation, elongation and termination. This complex process involves various cell signaling methods as well as the activity of many enzymes.…

    • 1359 Words
    • 6 Pages
    Improved Essays
  • Improved Essays

    Perhaps men are the better athletes. Perhaps men cannot be compared to women when it comes to athletics. Perhaps men will always be the dominant sex symbolized of power and strength. But no. Why are women always characterized as the weaker gender?…

    • 803 Words
    • 4 Pages
    Improved Essays
  • Great Essays

    Gene doping is defined in the Oxford Dictionary as “the transfer of genes or genetically modified cells into an individual as a potential method for illicitly enhancing athletic performance.” It is is a relatively new method of modifying the human genome for the purpose of increasing athletic performance. Gene doping can be traced back to research presented in the late 1990’s concerning genetic modification of skeletal muscles (Barton-Davis et al., 1998; McPherron et al., 1997). The research conducted by Burton Davis et al. (1998) has shown that with the while modifying certain genes, muscle fiber in the adult mice test cases have shown an increase of muscle mass and strength at around 15% compared to untreated mice.…

    • 1573 Words
    • 7 Pages
    Great Essays
  • Great Essays

    Speed In Sport Essay

    • 2340 Words
    • 10 Pages

    A genetic ceiling exist for the top speed an athlete can reach, therefore limiting the ability of the vast majority of people to become an Olympic 100-meter champion. However, while this ceiling exists, it is likely that few people actually reach their…

    • 2340 Words
    • 10 Pages
    Great Essays