Aldosterone and Hormone Replacement Therapy and Renal Dialysis

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Aldosterone and Hormone Replacement Therapy

Aldosterone falls in the class of hormone called mineralocorticoids, produces by the adrenal glands and is found near the kidneys. It sustains blood pressure, water and salt balance within the body. This procedure is assisting the kidneys to preserve sodium and excrete potassium in order to maintain a balance. If Aldosterone production falls, there isn’t enough regulation of salt and water balance (as aldosterone is being lost through urination) triggering blood pressure and blood volume to decline as a result of the kidneys not functioning properly. If body is in need of salt, water is not retained and adrenals release more Aldosterone and salt is reabsorbed from the tubule.

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Adrenal Insufficiency is treated orally through tablets taken once to three times per day depending on the individual’s case. The treatment is simply replacing the hormones that aren’t being produced. Cortisol is replaced with a synthetic glucocorticoid tablet taken 1-3 times daily. In cases where aldosterone levels are also scarce; it is then substituted with oral doses of a mineralocorticoid, fludrocortisone acetate, taken once or twice daily. Usually the patient is required to increase their salt intake and dosages of medications will be altered between individual patients.

While undertaking treatment an Addisonian crisis may occur resulting in life threatening occurrences; low blood pressure, low blood glucose, and high levels of potassium. In order for rapid movement throughout therapy intravenous (injections into veins) of glucocorticoids and saline solution with dextrose are administered. The patient is able t take fluids and medications by mouth, the procedure is reduced though low levels of aldosterone may include oral doses of fludrocortisone acetate. If an individual in undertaking surgery, they are required to be awake throughout the procedure and are treated with intravenous glucocorticoids and saline. Treatment may be needed for the surgery. During an illness

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