Akram Case Study

2194 Words 9 Pages
Akram was an 80 year old woman with a past medical history including hypertension, diverticulitis, TIA, and diabetes. Her history did include a serious head injury at the age of 45 from an automobile accident, but recovered well after some time in the hospital. As she aged she could remember childhood friends and family from 20+ years ago quite well. What tripped her up were simple daily processes of life. She might put food in the oven to cook but fail to turn it on after doing all the prep work or use the bathroom but not sit on the toilet, or forget what toilet paper was for. Suddenly in the middle of the day she might think she ought to remove her pants. She had been a very intelligent person, with a lot of energy and had previously been …show more content…
Driving was a big issue as well; she felt she could recall how but she got confused. She also frequently got lost on routine trips, like to the grocery. Additionally, she would forget whether she had eaten, and have several extra meals in a day unless a helper or family member was keeping track. She also gradually developed difficulty with finding the right word for a sentence. One day she was found wandering around her neighborhood, seemingly confused, during one of her morning walks. A good Samaritan asked her what was wrong, and she mentioned that she could not remember why she was outside, or the way to get home. The good Samaritan was worried about Akram and took her to the ER of a local hospital. After a brief hospital stay she was diagnosed with deep depression and discharged to a long-term care facility for monitoring. She remained at the long-term care facility where she continued to decline in function and memory. Akram died 3 months after being admitted to the ER. This paper will explore the causes of AD, the progression of the disease, and the possible reasons for increased risk among the …show more content…
AD is defined by presence of extracellular deposition of protein aggregates, intracellular accumulation of cytoskeletal elements, and synapse and neuronal loss. 7Deposition of (Aβ) in the walls of small arterioles occurs frequently.7 Intraneuronal aggregates containing Lewy bodies often coexist with AD changes. 7These features also seen with ADAD, though the nature and distribution are variable.7 Would be good to add a sentence in this section about why amyloid aggregates cause neuronal cell death. What exactly the amyloid deposits disrupt in the cell that causes neurons to

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